Synthesis of urea derivatives using multicomponent reactions of activated acetylene

Shams Najafi, Seyyed Jalal; Ghazvini, Maryam; Navabi, Atefeh

Manuscript ID : 697968 Visit : 133 Page: 3417 - 3420

Article Type: Original Research

Synthesis of urea derivatives using multicomponent reactions of activated acetylene

Subject Areas : Iranian Journal of Organic Chemistry

Seyyed Jalal Shams Najafi ¹ , Maryam Ghazvini ² , Atefeh Navabi ³

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Received: 2022-12-21 Accepted : 2022-12-21 Published : 2022-08-01

Keywords: Alcohol, Esterification, N-formylmorpholine, Acid chlorides, Potasium thiocyanate,

Abstract :

urea derivatives are obtained in good to excellent yields by proceeding through a simple, mild, and efficientprocedure utilizing activated acetylens, primary amines and isocyanates in the presence of catalytic amount of Nformylmorpholine under solvent-free conditions.

References:

Mechanistic Investigation of the [1+4] Cycloaddition Reaction Between Alkyl Isocyanides and 3-benzylidene-2,4-pentanedione: A Theoretical Study
Print Date : 2020-07-17
Synthesis and characterization of PTS and PDATS: Two maiden functionalized energetic polymers having tetrazole and triazine rings
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BF3 catalyzed hydroarylation reactions of arylsubstituted alkynes with different electron rich arenes
Print Date : 2014-11-01
Synthesis of some 3-indolyl heterocycles and evaluation of its antimicrobial activity
Print Date : 2016-08-01
1,3,4-Thiadiazole rings as π-spacers in triphenylamine based dyes: A density functional theory study of reactivity, UV/Visible spectra, structural and optical properties
Print Date : 2015-11-01
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Print Date : 2014-05-01

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Synthesis of urea derivatives using multicomponent reactions of activated acetylene