A green and efficient method for the preparation of 3, 4-dihydropyrimidin-2(1H)-ones using quaternary ammonium- treated clay in water
Subject Areas :Soheil Sayyahi 1 , Sedigheh Jahanbakhshi 2 , Zahra Dehghani 3
1 - 1Chemistry Department, Mahshahr Branch, Islamic Azad University, Mahshahr
2 - Chemistry Department, Omidieh Branch, Islamic Azad University, Omidieh, Iran
3 - Chemistry Department, Omidieh Branch, Islamic Azad University, Omidieh, Iran
Keywords: Biginelli reaction, Multicomponent reactions, organoclay, 3, 4-Dihydropyrimidin-2(1H)-ones,
Abstract :
In this study, a variety of 3, 4-dihydropyrimidin-2(1H)-ones derivatives were synthesized via three-component Biginelli reaction. The quaternary ammonium- treated clay -catalyzed process proved to be simple, efficient, and environmentally friendly.