SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 3-(2’-n-BUTYLBENZOFURAN-3’-YL)-5-ARYL-4, 5-DIHYDRO-1H-PYRAZOLES.

Subject Areas :

RAKESH P.N.ROSHAN ¹ , D.M. PUROHIT ² , SANDIP K.MATARIYA ³

1 - 1R.K.University, Rajkot, (Guj), India
2 - Shri M&N. Virani Science College, Department of Chemistry, Kalawad Road, Rajkot-390005, (Guj), India
3 - Smt.S.M.Panchal Science College, Department of Chemistry , Talod, (Guj), India

Received: 2018-11-07 Accepted : 2019-01-26 Published : 2019-03-01

Keywords: Antimicrobial, UTYLBENZOFURAN- PYRAZOLES- SYNTHESIS,

Abstract :

3-(2’-n-butylbenzofuran-3’-yl)-5-aryl-4, 5-dihydro-1H-pyrazoles (4a-4k) have been synthesized. The synthesized products have been assayed for their antimicrobial activity against Gram+ve, Gram-ve bacteria and fungi. All the synthesized products were assigned with IR, 1HNMR, Mass Spectra, TLC, and elemental analysis. Some of the products showed moderate activity, compare with known standard drugs.

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SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 3-(2’-n-BUTYLBENZOFURAN-3’-YL)-5-ARYL-4, 5-DIHYDRO-1H-PYRAZOLES.