Genetic Perspective of Ascites Syndrome in Meat-Type Chickens

Subject Areas : Camel

ج.  احمدپناه ¹ (Department of Animal Science, Faculty of Agricultural Science, University of Guilan, Rasht, Iran)
ع.ا.  شادپرور ² (Department of Animal Science, Faculty of Agricultural Science, University of Guilan, Rasht, Iran)
ن.  قوی حسین-زاده ³ (Department of Animal Science, Faculty of Agricultural Science, University of Guilan, Rasht, Iran)
ع.  پاکدل ⁴ (Department of Animal Science, College of Agriculture, Isfahan University of Technology, Isfahan, Iran)

Received: 2015-02-20 Accepted : 2015-10-31 Published : 2016-03-01

Keywords: ascites, genetic aspect, meat-type chickens, selection strategy,

Abstract :

Pulmonary hypertension syndrome (ascites) is a metabolic disorder in fast-growing broilers. Inconsistency of oxygen requirement and the cardiovascular ability make the birds susceptible to ascites. Incidence of ascites was accompanied by right ventricular hypertrophy, fluid accumulation in the abdominal cavity and finally mortality. The objective of the current study was to review the genetic basis of ascites syndrome and investigation of indicator traits of ascites syndrome to use in selection indices for reducing ascites susceptibility in broilers. Developing a breeding objective to increase body weight and to reduce ascites susceptibility in broilers is of ongoing interest, because the ascites syndrome is still a major challenge for poultry breeders. The blood gas parameters, which measured early in life, make it possible to design alternative selection schemes to reach birds resistance to ascites. In this way, ascites susceptibility can be effectively reduced but it might be comes at a cost, including a reduction in selection response for growth rate, due to genetic correlations. Based on the best combination of traits considered, reduction in gain for growth rate might be decreased, although with limited efficiency. Also, marker-assisted selection can be used effectively to reduce ascites susceptibility with respect to benefit-costs analysis.

References:

Anthony N.B., Balog J.M., Hughes J.D., Stamps L., Cooper M.A., Kidd B.D., Liu X., Huff G.R., Huff W.E. and Rath N.C. (2001). Genetic selection of broiler lines that differ in their susceptibility 1. Selection under hypobaric conditions. Pp. 327-328 in Proc. 13^th European Symp. Poult. Nutr. Blankenberge, Belgium.

Balog J.M., Anthony N.B., Kidd B.D., Liu X., Cooper M.A., Huff G.R., Huff W.E., Wideman R.F. and RathN.C. (2001). Genetic selection of broiler lines that differ in their ascites susceptibility 2. Response of the ascites lines to cold stress and bronchus occlusion. Pp. 329-330 in Proc. European Symp. Poult. Nutr. Blankenberge, Belgium.

Balog J.M., Kidd B.D., Huff G.R., Huff W.E., Rath N.C. and Anthony N.B. (2003). Effect of cold stress on broilers selected for resistance or susceptibility to ascites syndrome. Poult. Sci. 82, 1383-1387.

Closter A.M., Van As P., Groenen M.A.M., Vereijken A.L.J., Van Arendonk J.A.M. and Bovenhuis H. (2009). Genetic and phenotypic relationships between blood gas parameters and ascites-related traits in broilers. Poult. Sci. 88, 483-490.

Decuypere E., Buyse J. and Buys N. (2000). Ascites in broiler chickens: exogenous and endogenous structural and functional causal factors. World’s Poult. Sci. J. 56, 367-377.

Decuypere E., Hassanzadeh M. and Buys N. (2005). Further insights into the susceptibility of broilers to ascites. Vet. J. 169, 319-320.

De Greef K.H., Janss L.L., Vereijken A.L., Pit R. and Gerritsen C.L. (2001). Disease-induced variability of genetic correlations: ascites in broilers as a case study. J. Anim. Sci. 79, 1723-1733.

Dekkers J.C.M. and Hospital F. (2002). The use of molecular genetics in the improvement of agricultural populations. Nat. Rev. Genet. 22, 22-32.

Hassanzadeh M., Buys J., Toloe T. and Decuyper E. (2014). Ascites syndrome in broiler chickens: a review on the aspect of endogenous and exogenous factors interactions. J. Poult. Sci. 51, 229-241.

Hassanzadeh M., Maddadi M., Mirzaie S., Assasie K. and Moayyedian H. (2010). Partial pressure of carbondioxide in the venous blood of young birds as a predictor of ascites susceptibility in broiler chickens. Acta Vet. Hung. 58, 221-230.

Havenstein G.B., Ferket P.R. and Qureshi M.A. (2003). Growth, livability and feed conversion of 1957 versus 2001 broilers when fed representative 1957 and 2001 broiler diets. Poult. Sci. 82, 1500-1508.

Hoving-Bolink A.H., Kranen R.W., Klont R.E., Gerritsen C.L.M. and de Greef K.H. (2000). Fibre area and capillary supply in broiler breast muscle in relation to productivity and ascites. Meat Sci. 56, 397-402.

Julian R.J. and Mirsalimi S.M. (1992). Blood oxygen concentration of fast growing and slow-growing broiler chickens and chickens with ascites from right ventricular failure. Avian Dis. 36,730-732.

Krishnamoorthy S., Smith C.D., Al-Rubaye A.A., Erf G.F., Wideman R.F., Anthony N.B. and Rhoads D.D. (2014). A quantitative trait locus for ascites on chromosome 9 in broiler chicken lines. Poult. Sci. 93, 307-317.

Lubritz D.L., Smith J.L. and McPherson B.N. (1995). Heritability of ascites and the ratio of right to total ventricle weight in broiler breeder male lines. Poult. Sci. 74, 1237-1241.

Luger D., Shinder D., Wolfenson D. and Yahav S. (2003). Erythropoiesis regulation during the development of ascites syndrome in broiler chickens: a possible role of corticosterone on egg production. J. Anim. Sci. 81, 784-790.

McMillanI. and Quinton V.M. (2002). Selection strategies for limiting the increase in ascites while increasing growth in broilers. Poult. Sci. 81, 737-744.

Moghadam H.K., McMillan I., Chambers J.R. and Julian R.J. (2001). Estimation of genetic parameters for ascites syndrome in broiler chickens. Poult. Sci. 80, 844-848.

Navarro P., Visscher P.M., Chatziplis D., Koerhuis A.N.M. and Haley C.S. (2006). Genetic parameters for blood oxygen saturation, body weight and breast conformation in 4 meat-type chicken lines. Br. Poult. Sci. 47, 659-670.

Olkowski A.A., Krover D., Rathgeber B. and Classen H.L. (1999). Cardiac index, oxygen delivery and tissue oxygen extraction in slow and fast growing chickens, and in chickens with heart failure and ascites: a comparative study. Avian Pathol. 28, 137-146.

Olkowski A.A., Wajnarowicz C., Rathgeber B.M., Abbott J.A. and Classen H.L. (2003). Lesions of pericardium and their significance in the aetiology of heart failure in broiler chickens. Res. Vet. Sci. 74, 203-211.

Pakdel A. (2004). Genetic analysis of ascites related traits in broilers. Ph D. Thesis. WageningenUniv., Wageningen.

Pakdel A., Bijma P., Ducro B.J. and Bovenhuis H. (2005a). Selection strategies for body weight and reduced ascites susceptibility in broilers. Poult. Sci. 84, 528-535.

Pakdel A., Van Arendonk J.A.M., Vereijken A.L.J. and Bovenhuis H. (2005b). Genetic parameters of ascites-related traits in broilers: correlations with feed efficiency and carcass traits. Br. Poult. Sci. 46, 43-53.

Pakdel A., Van Arendonk J.A.M., Vereijken A.L.J. and Bovenhuis H. (2005c). Genetic parameters of ascites-related traits in broilers: effect of cold and normal temperature conditions. Br. Poult. Sci. 46, 35-42.

Pakdel A., Van Arendonk J.A.M., Vereijken A.L.J. and Bovenhuis H. (2002). Direct and maternal genetic effects for ascites-related traits in broilers. Poult. Sci. 81, 1273-1279.

Pavlidis H.O., Balog J.M., Stamps L.K., Hughes Jr J.D., Huff W.E. and Anthony N.B. (2007). Divergent selection for ascites incidence in chickens. Poult. Sci. 86, 2517-2529.

Rabie T.S.K.M. (2004). Pulmonary hypertension syndrome in chicken: Peeking under QTL peaks. Ph D. Thesis. WageningenUniv., Wageningen.

Scheele C.W., Decuypere E., Vereijken P.F.G. and Schreurs F.J.G. (1992). Ascites in broilers. 2. Disturbances in the hormonal regulation of metabolic rate and fat metabolism. Poult. Sci. 71, 1971-1984.

Scheele C.W., Van der Klis J.D., Kwakernaak C., Dekkers R.A., Van Middelkoop J.H., Buyse J. and Decuypere E. (2005). Ascites and venous carbon dioxide tensions in juvenile chickens of highly selected genotypes and native strains. World’s Poult. Sci. J. 61, 113-129.

Siegel P.B. and Dunnington E.A. (1997). Genetic selection strategies-population genetics. Poult. Sci. 76, 1062-1065.

Tekeli A. (2014). Effects of ascites on blood gas, blood oximetry parameters and heart sections of broilers growth at high altitude. J. Anim. Plant. Sci. 24, 998-1002.

Van As P., Elferink M.G., Closter A.M., Vereijken A., Bovenhuis H., Crooijmans R.P.M.A., Decuypere E. and Groenen M.A.M. (2010). The use of blood gas parameters to predict ascites susceptibility in juvenile broilers. Poult. Sci. 89, 1684-1691.

Wideman R.F. and French H. (2000). Ascites resistance of progeny from broiler breeders selected for two generations using chronic unilateral pulmonary artery occlusion. Poult. Sci. 79, 396-401.

Wideman R.F., Hooge D.M. and Cummings K.R. (2003). Dietary sodium bicarbonate, cool temperatures, and feed withdrawal: impact on arterial and venous blood-gas values in broilers. Poult. Sci. 82, 560-570.

Wideman R.F., Rhoads D.D., Erf G.F. and Anthony N.B. (2013). Pulmonary arterial hypertension (ascites syndrome) in broilers: a review. Poult. Sci. 92, 64-83.

Witzel D.A., Huff W.E., Kubena L.F., Harvey R.B. and Elissalde M.H. (1990). Ascites in growing broilers: a research model. Poult. Sci. 69, 741-745.

Zerehdaran S., Van Grevehof E.M., Van Der Waaij E.H. and Bovenhuis H. (2006). A bivariate mixture model analysis of body weight and ascites traits in broilers. Poult. Sci. 85, 32-38.