Clean synthesis of 1,8-dioxo-octahydroxanthene derivatives using NBS as an efficient and almost neutral catalyst in aqueous media

Subject Areas : Journal of the Iranian Chemical Research

Gholam Hossein Mahdavinia ¹

1 - Chemistry Department, Islamic Azad University, Marvdasht Branch, Marvdasht, Iran

Received: 2008-05-30 Accepted : 2008-09-17 Published : 2008-10-20

Keywords: 1, One-pot, NBS, 8-dioxo-octahydroxanthene, Organocatalyst, Aqueous media,

Abstract :

An efficient one-pot condensation for the synthesis of 1,8-dioxo-octahydroxanthene is achieved through a condensation of aryl aldehydes and 5,5-dimethyl-1,3-cyclohexandione in the presence of NBS. This method enjoys several advantages such as low cost, simple work up procedure and safe reaction condition. In addition, water was chosen as a green solvent.

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