Water as the Green Media for the Synthesis of Isoquinoline Derivatives

Pahlavan, Rokhsar; Najaf, Maedeh; Hossaini, Zinatossadat

Manuscript ID : 516070 Visit : 220 Page: 97 - 102

20.1001.1.20083815.2015.9.3.10.1

Article Type: Original Research

Water as the Green Media for the Synthesis of Isoquinoline Derivatives

Subject Areas : Polymer

Rokhsar Pahlavan ¹ , Maedeh Najaf ² , Zinatossadat Hossaini ³

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Received: 2015-11-10 Accepted : 2015-11-10 Published : 2015-07-01

Keywords:

Abstract :

An efficient synthesis of isoquinoline-2,3-dicarboxylates is described via one-pot reactions of isoquinoline and alkyl bromids with dialkyl acetylenedicarboxylates in water at 70oC. Themild reaction conditions and high yields of the products exhibit thegood synthetic advantageof these methods.

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Water as the Green Media for the Synthesis of Isoquinoline Derivatives