SiO2-BaCl2 as a Highly Efficient and Reusable Heterogeneous Catalyst for the One-pot Synthesis of 3,4-dihydropyrimidin-2-(1H)- one/thione Derivatives Under Solvent-free Conditions

Subject Areas : Polymer

Farhad Hatamjafari ¹

1 -

Received: 2015-11-11 Accepted : 2015-11-11 Published : 2015-01-01

Keywords:

Abstract :

An efficient protocol for the synthesis of 3,4-dihydropyrimidin-2-(1H)-one/thione derivatives via multi-component coupling reaction of aromatic aldehydes, β-ketoester and urea or thiourea under solvent-free conditions using Silica Supported Barium Chloride as a catalyst is described. All prepared compounds with melting points, IR,1H NMR and13C NMR were identified. High yields, mild conditions, easy availability and reusability were some advantages of this catalyst.