Green synthesis of thiazolo oxazin using multicomponent reactions of thiazole

Subject Areas : Iranian Journal of Organic Chemistry

Maryam Ghazvini ¹ , Parvaneh Firoozi Khanghah ² , Maryam Koohi ³

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Received: 2023-02-26 Accepted : 2023-02-26 Published : 2022-11-01

Keywords: thiazole, Phenacyl bromids, Activated acetylenic compounds, Thiazolooxazin,

Abstract :

In this research work, the reaction of activated acetylenic compounds, alkyl bromids and thiazole as nucleophileswas described that was led to synthesis of thiazolooxazine derivatives. Some advantages of this procedure are performingreactions in green media, easy separation of product and high yields of product.