Heterogeneous Catalyst for the One-Pot Synthesis of 1,8-Dioxodecahydroacridine

Subject Areas :

1 - Department of Chemistry, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran
2 - Department of Chemistry, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran

Received: 2018-09-07 Accepted : 2018-11-26 Published : 2018-11-20

Keywords: Solvent-free, Multicomponent, One-pot synthesis, Hantzsch, 8-Dioxohexahydroacridine, 1,

Abstract :

An efficient and environmental-friendly synthetic route to 1,8-dioxodecahydroacridines derivatives have been developed via multi-component one-pot Hantzsch reaction of various aldehydes and ammonium acetate with 2 equivalents dimedone in the presence of Phosphorus pentoxide supported on aluminaas catalyst under solvent-free conditions. The present approach offersseveral advantages such as short reaction times, easy isolation and purification of product, and safe, non-toxic, recyclable and economic use of catalyst.

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Heterogeneous Catalyst for the One-Pot Synthesis of 1,8-Dioxodecahydroacridine