Isolation and identification of bioactives organics compounds from the bark and seeds of Santaloïdes afzelii (Connaraceae)

Subject Areas : Phytochemistry: Isolation, Purification, Characterization

Amian Brise Benjamin Kassi ¹ , Coulibaly Aïssata Soro ² , Yaya Soro ³ , Koffi Julien Golly ⁴ , Siaka Sorho ⁵

1 - Laboratory of Organic Chemistry and Natural Substances (LCOSN), Félix Houphouet-Boigny University, 22 BP 582 Abidjan 22, Cote d’Ivoire
2 - Laboratory of Industrial Processes, Synthesis, Environment and New Energies, National Polytechnic Institute Felix Houphouët-Boigny, BP 1093 Yamoussoukro, Cote d’Ivoire
3 - Laboratory of Industrial Processes, Synthesis, Environment and New Energies, National Polytechnic Institute Felix Houphouët-Boigny, BP 1093 Yamoussoukro, Cote d’Ivoire
4 - Unit of Antibiotics, Natural Substances and Surveillance of the Resistance of Microorganisms to Anti-Infectives (ASSURMI) of the Department of Bacteriology of the Institut Pasteur Cote d’Ivoire (IPCI), 01 BP 490 Abidjan 01, Cote d’Ivoire
5 - Laboratory of Industrial Processes, Synthesis, Environment and New Energies, National Polytechnic Institute Felix Houphouët-Boigny, BP 1093 Yamoussoukro, Cote d’Ivoire

Received: 2019-07-15 Accepted : 2020-04-16 Published : 2020-06-01

Keywords: Gallic acid, Connaraceae, epi-Catechin, Staphylococcus aureus, Santaloïdes afzelii, Dimers procyanidins,

Abstract :

Santaloïdes afzelii (R.Br. ex Planch.) Schellenb (Connaraceae) is used in Africa as an analgesic, aphrodisiac and in the treatment of stomachaches, muscular pains and in medico magic rites. The present study aims to identify the bioactive organic compounds from the bark and seeds of Santaloïdes afzelii collected in Korhogo in the north of Côte d’Ivoire. Microbiological testing againts Staphylococcus aureus of the hydro ethanolic crude extracts of the bark and seeds showed low activities compared to the activities of oxacillin and cefoxitin. The chemical investigations of these extracts led to the identification of gallic acid, epi-catechin and dimers of procyanidin.

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