Delayed Ovarian Cyclicity Does not Reflect Blood Metabolites Irregularity in Postpartum Holstein Cows
Subject Areas : Camel
1 - Department of Theriogenology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt
Keywords: progesterone, blood metabolites, postpartum cows, reproductive indices,
Abstract :
An experiment was conducted to investigate the effect of different types of ovarian cycles on reproductive indices and blood metabolites in 61 Holstein cows. Blood samples were taken from each cow between day 12 and day 50 postpartum (PP). Serum progesterone concentrations were measured to determine the onset of luteal function and different types of luteal dysfunctions in cows. Serum glucose, cholesterol and blood urea nitrogen concentrations were measured in the cows with normal and abnormal ovarian cyclicity. In this study, 29 (47.5%) cows showed normal ovarian cyclicity with first luteal activity detected before day 50 days PP, whereas 32 (52.5%) cows showed abnormal cyclicity. Of the 32 cows with abnormal patterns, 13 (21.3%) had prolonged luteal phase (PLP), 7 (11.5%) had short luteal phase (SLP) and 12 (19.7%) had delayed first ovulation (delayed ovulation).Progesterone concentration at different times was considerably varied from day to another day (P≤0.01), while the main effect of the group on the progesterone concentration was significant (P≤0.01). Cows that had normal cyclicity showed earlier luteal activity (P≤0.01) and shorter interval to first ovulation (P≤0.01) compared to cows with abnormal cyclicity. There were no significant differences in different blood metabolites between cows with normal or abnormal cyclicity. In conclusion, a high percentage (52.5%) of the postpartum cows had abnormal ovarian cycles. The abnormal ovarian cycles reduced the reproductive performance of dairy cows, including the onset of luteal activity and interval to first ovulation. Blood metabolites were not associated with postpartum abnormal cycles in cows.
Agenas S., Heath M.F., Nixon R.M., Wilkinson J.M. and Phillips C.C. (2006). Indicators of under nutrition in cattle. Anim. Welf. 15, 149-160.
Ahmad I., Lodhi L.A., Qureshi Z.I. and Younis M. (2004). Studies on blood glucose, total protein, urea and cholesterol levels in cyclic, non cyclic and endometritic crossbred cows. Pakistan Vet. J. 24, 92-94.
Allain C.C., Poon L.S., Chan C.S.G., Richmond W. and Fu P.C. (1974). Enzymatic determination of total serum cholesterol. Clin. Chem. 20, 470-475.
Burle P.M., MangleN.S., Kothekhar M.D. and Kalorey D.R. (1995). Blood biochemical profiles during various reproductive states of Sahiwal and Jersey × Sahiwal cattle. Livest. Adv. 20(7), 13-20.
Butler W.R. (1998). Review: effect of protein nutrition on ovarian and uterine physiology in dairy cattle. J. Dairy Sci. 81(9), 2533-2539.
Diskin M.G., Mackey D.R., Roche J.F. and Sreenan J.M. (2003). Effects of nutrition and metabolic status on circulating hormones and ovarian follicle development in cattle. Anim. Reprod. Sci. 78, 345-370.
Hess B.W., LakeS.L., Scholljegerdes E.J., Weston T.R., Nayigihugu V., Molle J.D.C. and Moss G.E. (2005). Nutritional controls of beef cow reproduction. J. Anim. Sci. 83, 90-106.
Hommeida A., Nakao T. and Kubota H. (2005). Onset and duration of luteal activity postpartum and their effect on first insemination conception rate in lactating dairy cows. J. Vet. Med. Sci. 67(10), 1031-1035.
Jayachandran S., Nanjappan K., Muralidharan J., Selvaraj P. and Manoharan A. (2013). Blood biochemical and mineral status in cyclic and postpartum anestrus buffaloes. Int. J. Food Agric. Vet. Sci. 3, 93-97.
Jorritsma R., Wensing T., Kruip T., Vosa P. and Noordhuizen J. (2003). Metabolic changes in early lactation and impaired re-productive performance in dairy cows. Vet. Res. 34, 11-26.
Lamming G.E. and Darwash A.O. (1998). The use of milk progesterone profiles to characterise components of subfertitlity in milked dairy cows. Anim. Reprod. Sci. 52, 175-190.
Leroy J.L.M.R., Vanholder T., Delanghe J.R., Opsomer G., Van Soom A., Bols P.E.J., Dewulf J. and de Kruif A. (2004). Metabolic changes in follicular fluid of the dominant follicle in high-yielding dairy cows early post partum. Theriogenology. 62(6), 1131-1143.
Leroy J.L.M.R., Vanholder T., Van Knegsel A.T.M., Garcia-IspiertoI. and Bols P.E.J. (2008). Nutrient prioritization in dairy cows early postpartum: mismatch between metabolism and fertility? Reprod. Domest. Anim. 43, 96-103.
Lindsay D.B., Hunter R.A., Gazzola C., Spiers W.G. and Sillence M.N. (1993). Energy and growth. Australian J. Agric. Res. 44, 875-889.
Lucy M.C. (2008). Functional differences in the growth hormone and insulin-like growth factor axis in cattle and pigs: implications for post-partum nutrition and reproduction. Reprod. Domest. Anim. 43, 31-39.
Maciel S.M., Chamberlain C.S., Wettemann R.P. and Spicer L.J. (2001). Dexamethasone influences endocrine and ovarian function in dairy cattle. J. Dairy Sci. 84, 1998-2009.
Majeed M.A., Iqbal J. and Chaudhry M.N. (1990). Blood chemistry of clinical merits in Nili-Ravi buffaloes of two age groups and at two stages of lactation. Pakistan Vet. J. 10(2), 55-59.
Ndlovu T., Chimonyo M., Okoh A.I., Muchenje V., Dzama K. and Raats J.G. (2007). Review: assessing the nutritional status of beef cattle: current practices and future prospects. African J. Biotechnol. 6(24), 2727-2734.
Opsomer G., Coryn M., Deluyker H. and de Kruif A. (1998). An analysis of ovarian dysfunction in high yielding dairy cows after calving based on progesterone profiles. Reprod. Domest. Anim. 33, 193-204.
Pambu-Gollah R., Cronje P.B. and Casey N.H. (2000). An evaluation of the use of blood metabolite concentrations as indicators of nutritional status in free-ranging indigenous goats. South African J. Anim. Sci. 30, 115-120.
Pedron O., Cheli F., Senatore E., Baroli D. and Rizzi R. (1993). Effect of body condition score at calving on performance, some blood parameters, and milk fatty-acid composition in dairy-cows. J. Dairy Sci. 76(9), 2528-2535.
Saleh N., Mahmud E. and Waded E. (2011). Interactions between insulin like growth factor 1, thyroid hormones and blood energy metabolites in cattle with postpartum inactive ovaries. Nat. Sci. 9(5), 56-63.
Shrestha H.K., Nakao T., Suzuki T., Akita M. and Higaki T. (2005). Relationships between body condition score, body weight, and some nutritional parameters in plasma and resumption of ovarian cyclicity postpartum during pre-service period in high-producing dairy cows in a subtropical region in Japan. Theriogenology. 64, 855-866.
Shrestha H.K., Nakao T., Suzuki T., Higaki T. and Akita M. (2004). Effects of abnormal ovarian cycles during pre-service period postpartum on subsequent reproductive performance of high-producing Holstein cows. Theriogenology. 61, 1559-1571.
SPSS Inc. (2011). Statistical Package for Social Sciences Study. SPSS for Windows, Version 20. Chicago SPSS Inc.
Tabacco A., Meiattini F., Moda E. and Tarli P. (1979). Simplified enzymic / colorimetric serum urea nitrogen determination. Clin. Chem. 25(2), 336-337.
Tamadon A., Kafi M., Saeb M., Mirzaei A. and Saeb S. (2011). Relationships between insulin-like growth factor-I, milk yield, body condition score, and postpartum luteal activity in high-producing dairy cows. Trop. Anim. Health Prod. 43, 29-34.
Trinder P. (1969). Determination of glucose in blood using glucose oxidase with an alternative oxygen receptor. Ann. Clin. Biochem. 6, 24.
Westwood C.T., Lean I.J. and Kellaway R.C. (1998). Indications and implications for testing of milk urea in dairy cattle: a quantitative review. Part 2. Effect of dietary protein on reproductive performance. New Zealand Vet. J. 46(4), 123-130.
Wettemann R.P., Lents C.A., Ciccioli N.H., White F.J. and RubioI. (2003). Nutritional and suckling mediated anovulation in beef cows. J. Anim. Sci. 81(2), 48-59.
Yotov S.A., Atanasov A.S. and Ilieva Y.Y. (2013). Relationship of some blood serum parameters with reproductive performance of bulgarian murrah buffaloes after hormonal treatment during the early postpartum (preliminary study). J. Vet. Adv. 3(5), 160-164.