Number 2 Volume 4

Open Access Article

1 - Novel synthesis of Pyrimido[4,5- e] [1,3,4] thiadiazines
Abdolhassan Doulah

Treatment of 1-(5-bromo-2-chloro-6-methylpyrimidin-4-yl)-1-methylhydrazine with dimethylthiocarbamoylchloride gave 7-chloro-N,N,1,5-tetramethyl-1H-pyrimido[4,5-e][1,3,4]thiadiazin-3-amine in basic acetonitrile. The latter compounds were reacted with secondary amines in More

Treatment of 1-(5-bromo-2-chloro-6-methylpyrimidin-4-yl)-1-methylhydrazine with dimethylthiocarbamoylchloride gave 7-chloro-N,N,1,5-tetramethyl-1H-pyrimido[4,5-e][1,3,4]thiadiazin-3-amine in basic acetonitrile. The latter compounds were reacted with secondary amines in boiling ethanol to afford the related 7-amino derivatives. Manuscript profile

Open Access Article

2 - Aminolysis of selected methylpyrimidines in protic solvents
Hossein Eshtiagh-Hosseini Masoud Mirzaei

Crystallographic data analyses indicate that three types of prolinium cations, along with two types of hydrogen bonding, produce and stabilize the helical structure of triprolinium 12-phosphomolybdate. There are similarities between this organic-inorganic compound and p More

Crystallographic data analyses indicate that three types of prolinium cations, along with two types of hydrogen bonding, produce and stabilize the helical structure of triprolinium 12-phosphomolybdate. There are similarities between this organic-inorganic compound and peptides/proteins. The stronger “conventional” hydrogen bonds and the less common C-H…O attractions play critical roles in generating and stabilizing the DNA-like network. Manuscript profile

Open Access Article

3 - arylaminotetrazoles : via [2+3] cycloaddition of nitriles and sodium azide via solid acid catalysis
Abbas Teimouri Alireza Najafi Chermahini

The [3+2] cycloaddition between various nitriles and sodium azide proceeds smoothly in the presence of zeolite and sulfated Zircona as effective catalyst and in the water and DMF/MeOH, to give the corresponding arylaminotetrazoles in good to high yields. The reaction mo More

The [3+2] cycloaddition between various nitriles and sodium azide proceeds smoothly in the presence of zeolite and sulfated Zircona as effective catalyst and in the water and DMF/MeOH, to give the corresponding arylaminotetrazoles in good to high yields. The reaction most probably precedes through the in situ formation of a catalyst azide species, followed by a successive [3+2] cycloaddition with the nitriles. This method has the advantages of high yields, simple methodology,and easy work-up. The catalyst can be recovered by simple filtration and reused in good yields Manuscript profile

Open Access Article

4 - conformational properties and the anomeric effect study of phosphinanes
Javad Azizian Mahdieh Entezari Hossein Anaraki Ardakani Shahab Zomorodbakhsh

Ab initio HF/6-31G* Methode was employed to calculate the bond length in 2- phosphinanes when electronegative groups was at C-2 tend axial and equatorial positions. The magnitude of the anomeric effect depends on the nature of the substituent, the effect of the substitu More

Ab initio HF/6-31G* Methode was employed to calculate the bond length in 2- phosphinanes when electronegative groups was at C-2 tend axial and equatorial positions. The magnitude of the anomeric effect depends on the nature of the substituent, the effect of the substituent can be seen by comparing the bond length in 2-chloro and 2- boromo substituented phosphinanes. The effect of anomeric effect have been effected on the bond length in 2-phosphinanes. Manuscript profile

Open Access Article

5 - preparation of 3, 4-dihydropyrimidin-2(1H)-ones using quaternary ammonium- treated clay in water
Soheil Sayyahi Sedigheh Jahanbakhshi Zahra Dehghani

In this study, a variety of 3, 4-dihydropyrimidin-2(1H)-ones derivatives were synthesized via three-component Biginelli reaction. The quaternary ammonium- treated clay -catalyzed process proved to be simple, efficient, and environmentally friendly.

In this study, a variety of 3, 4-dihydropyrimidin-2(1H)-ones derivatives were synthesized via three-component Biginelli reaction. The quaternary ammonium- treated clay -catalyzed process proved to be simple, efficient, and environmentally friendly. Manuscript profile

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