• فهرست مقالات Lantana camara

      • دسترسی آزاد مقاله

        1 - Analysis of the correlation between phytochemical content and wound-healing potential of Lantana camara ethyl acetate and methanol extracts
        آیرین آگبو بوییسوا هلانگوتی جنسکه دیدلوف آنا هاتینگ لاون ونابلس شارلین گووندر مارینا ون دی ونتر
        Background & Aim: Lantana camara, regarded as an invasive plant, is found in tropical climates worldwide. Several studies have validated its antiulcer activity which is one of the ethnomedicinal uses of L. camara. This study seeks to find the correlation between the چکیده کامل
        Background & Aim: Lantana camara, regarded as an invasive plant, is found in tropical climates worldwide. Several studies have validated its antiulcer activity which is one of the ethnomedicinal uses of L. camara. This study seeks to find the correlation between the phytochemical content and the wound-healing potential of L. camara extracts.Experimental: The study was conducted using spectrophotometric analysis and selected in vitro bioactivity assays; 3-[4,5-dimethylthiazole-2-yl]-2,5-diphenyltetrazolium bromide (MTT), inhibitory effect on nitric oxide production in lipopolysaccharide-activated RAW 264.7 macrophages, and 96-well plate micro-broth dilution method assay, of methanol flower (MLF), berry (MLB), leaf (MLL) and ethyl acetate flower (ELF), berry (ELB), leaf (ELL) extracts for cytotoxicity, anti-inflammatory and antimicrobial activities which support wound-healing capabilities.Results: The highest total polyphenolic content (TPC) was recorded in MLF and ELF extracts (34.59±3.01; 29.50±2.11, mg GAEQ/100 mg). MLF and MLB retained the highest terpenoid concentration (20.74±2.34; 20.51±1.86 mg LIN EQ/100 mg). ELB exhibited anti-inflammatory activity at 200 μg/mL. MLF and ELB were nontoxic to Vero cells, while MLL and MLB caused < 20 % cell death at all concentrations investigated. All ethyl acetate extracts exhibited potent antimicrobial activities against Streptococcus pyogenes with both ELL and ELF extracts demonstrating inhibition with MIC ≤ 0.125 mg/mL. The results showed MLF which retained the highest TPC was nontoxic whereas ELL, with relatively high alkaloid content, was the most cytotoxic extract that exhibited growth inhibition to S. pyogenes at a significantly low MIC. Thus, the phytochemical content of extracts is positively associated with bioactivity. The nontoxic, anti-inflammatory, and antimicrobial activities support the wound-healing potentials of the extracts.Recommended applications/industries: The high phenolic content and microbial growth inhibition exhibited could be leveraged to develop wound-healing tinctures or isolate bioactive compounds that could be developed as wound-healing agents. پرونده مقاله
      • دسترسی آزاد مقاله

        2 - Micropropagation of <i>Lantana camara</i> Through Axillary Shoots Proliferation
        Ehsan Naderi Samani Zohreh Jabbarzadeh Cyrus Ghobadi
        In vitro budinduction and shoot regeneration of Lantana camara L. was investigated using axillary nodal explants. Multiple shoot buds were induced on Murashige and Skoog (MS) media supplemented with 0, 2, 4 and 8 mg/l of 6-benzylaminopurine (BAP) or thidiazuron (TDZ) fo چکیده کامل
        In vitro budinduction and shoot regeneration of Lantana camara L. was investigated using axillary nodal explants. Multiple shoot buds were induced on Murashige and Skoog (MS) media supplemented with 0, 2, 4 and 8 mg/l of 6-benzylaminopurine (BAP) or thidiazuron (TDZ) for proliferation and 0, 0.25 and 0.5 mg/l indole-3 butyric acid (IBA) for rooting. After 4 weeks, a maximum number of shoot buds was achieved on MS media containing 8 mg/l BAP and most buds were resulted in 8 mg/l TDZ. The results showed that the maximum length of shoots, internode length and weight were observed in MS media without any growth regulators. Suitable concentrations of cytokinins significantly increased RNA, DNA and protein synthesis and shoot induction. Difference in concentrations of BAP can be under the influence of genetic factors and experimental condition. Very low concentrations of TDZ stimulated the proliferation of lateral shoots in woody plants. Receptor molecules of TDZ had high affinity with this growth regulator. In this research, the highest number of roots was induced in MS media with 0.25 mg/l IBA. IBA is one of the strong PGRs in culture medium for stimulating and increasing the number of roots. IBA increases internal IAA, which is necessary for normal growth of root meristems and final development of roots. One of the effects of auxins is elongation of cells, but root cells need lower auxin for growth because auxin induces ethylene which is a root growth inhibitory. پرونده مقاله