• فهرست مقالات Cooperative catalyst

      • دسترسی آزاد مقاله

        1 - Synthesis and in vitro antibacterial study of dihydropyrano[3,2-c]chromene derivatives by nano fluoro apatite doped with Mg and Si as a cooperative catalyst
        Elmira Jahangard Leila Khazdooz Amin Zarei
        One of the important Multi-component reaction (MCRs) is the synthesis of dihydropyrano chromene derivatives by one-pot reaction. In this research, an inexpensive and effective one pot three component procedure with good yields for the synthesis of dihydro pyrano chromen چکیده کامل
        One of the important Multi-component reaction (MCRs) is the synthesis of dihydropyrano chromene derivatives by one-pot reaction. In this research, an inexpensive and effective one pot three component procedure with good yields for the synthesis of dihydro pyrano chromenes is reported. In this method, the synthesis of pyrano chromene derivatives was followed by using 4-hydroxycoumarin, malononitrile and aldehydes in the presence of catalytic amount of nano fluoro apatite doped with Mg and Si (Mg-Si-FA). It should be cited that all reactions were carried out in H2O/EtOH as the solvent under reflux condition and the corresponding products were obtained in good yields and pretty short reaction time. Moreover, the anti-bacterial properties of the present products were studied by determination of their minimum inhibitory concentration (MIC). پرونده مقاله