• فهرست مقالات Chemotaxonomy

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        1 - Chemical profiling of the fruits of <i>Styrax officinalis</i> L. from Monti Lucretili (Latium region, Central Italy): Chemotaxonomy and nutraceutical potential
        Alessandro Venditti Claudio Frezza Ilaria Serafini Sabina Pulone Giorgina Scardelletti Fabio Sciubba Armandodoriano Bianco Mauro Serafini
        In this work, the first phytochemical analysis ever performed on the fruits of Styrax officinalis L. (Styracaceae) collected from a population vegetating in the Mounts Lucretili National Park (Italy) was reported. Fifteen compounds were identified: tri-&alpha;-linolenoy چکیده کامل
        In this work, the first phytochemical analysis ever performed on the fruits of Styrax officinalis L. (Styracaceae) collected from a population vegetating in the Mounts Lucretili National Park (Italy) was reported. Fifteen compounds were identified: tri-&alpha;-linolenoyl-sn-glycerol (1), 1,2-di-&alpha;-linolenoyl-3-linoleoyl-sn-glycerol (2), 1-&alpha;-linolenoyl-2-palmitoyl-sn-glycerol (3), 1,2-di-&alpha;-linolenoyl-sn-glycerol (4), egonol (5), demethylegonol (6), homoegonol (7), 1,5-anhydro-D-mannitol (8), glucose (9), sucrose (10), 6''''-O-benzoyl-sucrose (11), raffinose (12), lactic acid (13), succinic acid (14) and glutamic acid (15). These compounds belong to seven different classes of natural metabolites and most of them have chemotaxonomic relevance. Moreover, S. officinalis might be an useful source of enantiopure 1,5-anhydro-D-mannitol which has several medicinal potentialities and is a versatile building block in organic synthesis, in particular for what concern the &ldquo;Green&rdquo; approaches, of valuable and potentially biologically active molecules. The presence of compounds (1-15) provides also a phytochemical rationale for the ancient ethnopharmacological uses of the species and affords evidences on its nutraceutical potentialities even for their consumption as food in human nutrition as it actually happens for animals. پرونده مقاله
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        2 - Phytochemical characteristics of <i>Galeopsis ladanum</i> subsp. <i>angustifolia</i> (Ehrh. ex Hoffm.) Gaudin collected in Abruzzo region (Central Italy) with chemotaxonomic and ethnopharmacological implications
        Claudio Frezza Alessandro Venditti Ilaria Serafini Alessandra Carassiti Sebastiano Foddai Armandodoriano Bianco Mauro Serafini
        In this work, a phytochemical analysis on the total aerial parts of Galeopsis ladanum subsp. angustifolia (Ehrh. ex Hoffm.) Gaudin collected in Abruzzo region (Central Italy) has been reported. Nine compounds were identified belonging to five different classes of natura چکیده کامل
        In this work, a phytochemical analysis on the total aerial parts of Galeopsis ladanum subsp. angustifolia (Ehrh. ex Hoffm.) Gaudin collected in Abruzzo region (Central Italy) has been reported. Nine compounds were identified belonging to five different classes of natural compounds. Additional chemotaxonomic markers were recognized than our previous study, as well. Their presence is perfectly in accordance with the current botanical classification of the species and shows the possibility of a pronounced metabolic variability. The observed phytochemical composition may also suggest the possible use of this species in the ethnopharmacological field just like most Galeopsis species since they are endowed with several medicinal properties. Furthermore, no potential toxic component was identified in the studied accession. پرونده مقاله
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        3 - Secondary metabolites of <i>Hypericum richeri</i> Vill. collected in Central Italy: chemotaxonomy and ethnomedicinal relevance
        Alessandro Venditti Armandodoriano Bianco
        The results of the phytochemical analysis of a Hypericum richeri Vill. accession collected from a population living in Appennines, Central Italy, are reported in this paper. The secondary metabolites pattern resulted mainly composed of flavonoids as both aglycones and i چکیده کامل
        The results of the phytochemical analysis of a Hypericum richeri Vill. accession collected from a population living in Appennines, Central Italy, are reported in this paper. The secondary metabolites pattern resulted mainly composed of flavonoids as both aglycones and in glycosidic form, such as quercetin (2), quercetin-3-O-methyl ether (3), 5,7,3&prime;,5&prime;-tetrahydroxyflavanone (8), isorhamnetin glucoside (7), isoquercitrin (9), hyperoside (10), quercitrin (11) and myricetin-3-O-rutinoside (12). It was also observed the presence of the naphtodianthrones hypericin (5) and pseudohypericin (6) together with organic acids (benzoic acid (4)), a glycolipid (2S)-1,2-di-O-[(9Z,12Z,15Z)-octadeca-9,12,15-trienoyl]-3-O-&beta;-D-galactopyranosyl glycerol (1) and the saccharides glucose (13), galactose (14) and sucrose (15). Among these constituents, compounds (1) and (3) have been identified in H. richeri Vill. for the first time during this study. The other difference in composition observed in the present study in respect to population from different regions is the absence of hyperforin and caffeoylquinic derivatives. The observed chemovariability, already reported in H. perforatum L., might be derived fromthe environmental characteristic of the collection site. The chemotaxonomic aspects, together with the pharmacologic relevance in traditional medicine of the isolated compounds were also discussed. پرونده مقاله
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        4 - The genus <i>Micromeria</i> Benth.: An overview on ethnobotany, chemotaxonomy and phytochemistry
        Majid Mohammadhosseini Alessandro Venditti Guido Flamini Satyajit Sarker Mohammadreza Kalaee
        The genus Micromeria Benth. from the family Lamiaceae mainly comprises herbaceous plants having several remarkable ethnobotanical, biological and phytochemical applications. This review critically appraises all the information available in the literature, e.g., Scopus, چکیده کامل
        The genus Micromeria Benth. from the family Lamiaceae mainly comprises herbaceous plants having several remarkable ethnobotanical, biological and phytochemical applications. This review critically appraises all the information available in the literature, e.g., Scopus, Institute for Scientific Information-Web of Science (ISI-WOS) as well as Medline on various species of this genus covering aspects of biological activity, ethnobotanical, chemical taxonomy and phytochemistry. The phytochemical composition of both essential oils and non-volatile extracts is reported. Their chemotaxonomic implications and ethnomedicinal impacts are also discussed. The pharmacological properties of crude extracts and isolated phytochemicals from Mircomeria spp. observed in several bioactivity tests are also critically reviewed. From phytochemical point of view, the characterization of the organic extracts of different Mircomeria spp. has led to the identification of some valuable natural compounds. Furthermore, the chemical profiles of most of the species are dominated by oxygenated monoterpenes. A wide spectrum of promising biological properties have been attributed to Mircomeria species including antibacterial, antifungal, antioxidant, anticholinesterase, tyrosinase inhibition and antinociceptive activities. Moreover, it has been shown that rosmarinic acid serves as a marker compound in several entities of this genus. پرونده مقاله
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        5 - Flavonoids from two Turkish <i>Centaurea</i> species and their chemotaxonomic implications
        Sharmeen Uddin Lillian Alnsour Peter Segun Huseyin Servi Sezgin Celik R. S&uuml;leyman G&ouml;kt&uuml;rk Afaf Al-Groshi Shaymaa Al-Majmaie Stephanie T. Guetchueng Lutfun Nahar Nicola M. Dempster Fyaz M. D. Ismail Kenneth J. Ritchie Satyajit D. Sarker
        Centaurea asutro-anatolica Hub.-Mor. and C. kizildaghensis Uzunh., E. Doğan &amp; H. Duman, two indigenous perennial herbs from the Turkish flora, belong to the medicinally important genus Centaurea L. (fam: Asteraceae), which comprises ca. 600 species worldwide. While چکیده کامل
        Centaurea asutro-anatolica Hub.-Mor. and C. kizildaghensis Uzunh., E. Doğan &amp; H. Duman, two indigenous perennial herbs from the Turkish flora, belong to the medicinally important genus Centaurea L. (fam: Asteraceae), which comprises ca. 600 species worldwide. While various Centaurea species are well-known for producing alkaloids, flavonoids, lignans and terpenoids, there is no report on any thorough phytochemical work on any of these two species available to date. In continuation of our phytochemical and bioactivity studies on the Turkish Centaurea species, four flavonoids apigenin (1), apigenin 7,4&rsquo;-dimethyl ether (2), genkwanin (3) and quercetin (4) were isolated from the methanol extracts of the aerial parts of C. austro-anatolica and C. kizildaghensis, for the very first time. The structures of the flavonoids were elucidated conclusively by spectroscopic means, i.e., UV, MS and 1D and 2D NMR data analyses. The distribution of these flavonoids (1-4) within the genus Centaurea and their possible chemotaxonomic implications within the genus Centaurea or the family Asteraceae have been discussed. پرونده مقاله