بررسی مقایسه‌ای اثرات ضد اضطرابی دمنوش چای سیاه با سنبل الطیب در موش‌های صحرایی ماده
محورهای موضوعی :
فصلنامه زیست شناسی جانوری
منوچهر یوسفی
1
(گروه علوم دامی، دانشکده کشاورزی، مجتمع آموزش عالی سراوان، سراوان، ایران)
تاریخ دریافت : 1402/03/30
تاریخ پذیرش : 1402/05/12
تاریخ انتشار : 1402/12/01
کلید واژه:
اضطراب,
موش صحرایی,
چای سیاه,
سنبل‌الطیب,
ماز بعلاوه‌ای شکل مرتفع,
چکیده مقاله :
اضطراب یک اختلال شایع است که افراد زیادی در جامعه به آن مبتلا هستند و با علائم فیزیولوژیک مانند تاکیکاردی، تعریق، اختلال تنفسی، احساس بی‌حسی و گاهی فلج اندام‌ها و غیره همراه است. در این مطالعه اثرات ضد اضطرابی دمنوش چای سیاه (Camellia sinensis) در مقایسه با دمنوش سنبل‌الطیب (Valeriana sisymbriifolium) در موش‌های صحرایی ماده مورد ارزیابی قرار گرفت برای این کار از تعداد 21 سر موش صحرایی ماده به وزن 150 الی 200 گرم استفاده شد. حیوانات به سه گروه هفت‌تایی شامل کنترل، دریافت کننده سنبل‌الطیب و دریافت کننده چای سیاه تقسیم‌بندی شدند. در طول 24 ساعت قبل از تست سنجش اضطراب، گروه‌های آزمایشی به ترتیب دمنوش سنبل‌الطیب و چای سیاه با دوز 3/0 درصد دریافت کردند و گروه کنترل به‌جای دمنوش، آب آشامیدنی دریافت نمود. سپس رفتار موش‌ها در جهت بررسی اضطراب، فعالیت حرکتی به مدت ٥ دقیقه در یک ماز بعلاوه‌ای شکل مرتفع مورد ارزیابی قرار گرفت. نتایج به‌دست‌آمده با استفاده از آزمون تحلیل واریانس یک‌طرفه مورد مقایسه قرار گرفتند. بر اساس یافته‌های این مطالعه، بین رفتارهای شبه اضطرابی دمنوش چای سیاه نسبت به گروه سنبل‌الطیب هیچگونه اختلاف معنی داری مشاهده نگردید. به نظر می رسد که دمنوش سنبل‌الطیب در موش‌های صحرایی ماده نه تنها دارای اثرات ضداضطرابی نمی باشد بلکه هیچ برتری هم نسبت به چای سیاه ندارد.
چکیده انگلیسی:
Anxiety is a common disorder that many people in the society suffer from and is associated with physiological symptoms such as tachycardia, sweating, breathing disorder, feeling numb and sometimes paralysis of limbs, etc. In this study, the anti-anxiety effects of black tea (Camellia sinensis) were evaluated compared to Valerian sisymbriifolium herbal tea in female rats. For this work, 21 female rats weighing 150-200 grams were used. The animals were divided into 3 groups of seven including control, hyacinth recipient and black tea recipient. During the 24 hours before the anxiety test, the experimental groups received valerian tea and black tea with a dose of 0.3%, respectively, and the control group received drinking water instead of herbal tea. Then, the behavior of the mice was evaluated in order to investigate anxiety, motor activity for 5 minutes in an elevated plus-shaped maze. The obtained results were compared using the one-way analysis of variance test. Based on the findings of this study, no significant difference was observed between the anxiety-like behaviors of the black tea group compared to the valerian group. It seems that valerian tea in female rats not only does not have anti-anxiety effects, but also has no superiority over black tea.
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