بررسی تاثیر پاستوریزاسیون آغوز بر انتقال ایمنی غیرفعال در گوساله های نوزاد

محورهای موضوعی : آسیب شناسی درمانگاهی دامپزشکی

مسعود میلاندرزاده ¹ (دانش‌آموخته دانشکده دامپزشکی، واحد کرج، دانشگاه آزاد اسلامی، کرج، ایران)
سعید عظیم پور ² (استادیار گروه علوم درمانگاهی، دانشکده دامپزشکی، واحد بابل، دانشگاه آزاد اسلامی، بابل، ایران)

تاریخ دریافت : 1394/06/26 تاریخ پذیرش : 1395/03/05 تاریخ انتشار : 1395/03/01

کلید واژه: گوساله نوزاد, آغوز, پاستوریزاسیون, ایمنی غیرفعال,

چکیده مقاله :

چکیده ازآنجایی کهایمنوگلوبولین هادرمقادیربسیاراندکازطریقجفتاز مادربهگوساله هامنتقلمی شوند،انتقالایمنوگلبولین هاازطریقآغوزبهگوسالهازاهمیتبسیارزیادیبرخورداراست.نقصدرانتقالایمنیغیرفعالیکیازعواملاصلیمستعد کنندهبیماری هایمختلفبه خصوصاسهالدرگوساله هاینوزادمحسوبمی شود. بااینوجودبه علتحضوربرخیعواملبیماری زادرآغوزبه خصوصباکتری ها، برخی ازمحققیناستفادهازآغوزحرارت دیدهراتوصیهمی نمایند. کاهشباکتری هایبیماری‌زایموجوددرآغوزتحتتاثیرحرارتممکناستسببافزایشجذبایمنوگلبولین‌هاشود. برخیشواهدگویایکاهشجذبایمنو گلبولین هابه دنبالحرارتدادنآغوزمی باشند. هدف از این مطالعه، بررسیمیزانآلبومین،گلوبولینوپروتئینتامخوندرگوساله هاپسازحرارتدادنآغوزدردمای63درجهسلسیوس بهمدت30دقیقهمی باشد.بدینمنظور، دریکدامداری‌ صنعتیتعداد28رأسگوسالهنوزادبهدوگروهشاهدوتیمارتقسیمشدند.بهگوساله‌هایگروهشاهد آغوزمعمولیوبهگروهتیمارآغوزحرارت دیدهخوراندهشد.ازتمامیگوساله‌هایشاهدوتیماربلافاصلهپساززایشو48ساعتپسازآنخون گیریبه عملآمد.غلظتپروتئینتاموگلوبولیندرگروهشاهددرمقایسهباگروهتیماربیشتربود (05/0p<).تفاوتمعنی داریدرغلظتآلبومیندردوگروهمشاهدهنگردید. کاهشغلظتگلبولینسرمدرگروهتیماررامی تواندناتورهشدنگلوبولین هادر اثرحرارتدانست.

چکیده انگلیسی:

In cattle, small quantity of immunoglobulins is transferred to fetus through the placenta, so their transfer from colostrum is very important. Failure of passive immunity transfer is one of the main factors causing the susceptibility of newborn calves to various diseases, especially diarrhoea. However, due to the presence of some pathogens, especially bacteria in colostrum, some researchers recommend the use of heated colostrum. The reduction of pathogenic bacteria in heated colostrum may increase immunoglobulins absorption. However, some evidence indicate that immunoglobulin absorption was reduced after heating colostrum. The aim of this study was to compare serumic levels of albumin, total protein, and total globulin in the blood of newborn calves, before and after feeding of heated colostrum at 63˚C for 30 minutes. For this purpose, 28 newborn calves were divided into two groups of control and treatment. Two liters of heated colostrum was fed to the treatment group twice a day and the same amount of normal colostrum was given to the control group. Blood samples were taken of all calves immediately after birth and 48 hours after that. The results showed a higher concentration of total protein and globulin in the control group in comparison to the treatment group (p<0.05). There was no significant difference in albumin concentration.  Lower concentration of total protein and globulin is probably due to   denaturation of globulins.

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