Study of oxidation coupling of thiols to disulfides with Tripropylammonium fluorochromate (VI) (TriPAFC) in convenient and microwave conditions
محورهای موضوعی : Journal of Chemical Reactivity and Synthesis
Mohammad hosein farjam
1
(Department of Chemistry, Firoozabad Branch, Islamic Azad University, Firoozabad, Iran)
Amal Berisam
2
(Department of Chemistry, Ahvaz Branch, Islamic Azad University, Ahvaz, Iran)
کلید واژه: Oxidation, Microwave irradiation, thiol, Disulfide, Tripropylammonium fluorochromate, Solution,
چکیده مقاله :
Tripropylammonium fluorochromate is an efficient and new reagent, which prepares easily and oxidizes thiols to the corresponding disulfides quickly. The reactions perform cleanly and controlled to stop at the disulfide stage without over-oxidation side products. Coupling of thiols to their corresponding disulfides studied in solution at room temperature and in solution under microwave radiation. The easy procedure, simple work-up, short reaction times, and excellent yields are another advantages of this reagent.
