A green and efficient method for the preparation of 3, 4-dihydropyrimidin-2(1H)-ones using quaternary ammonium- treated clay in water

محورهای موضوعی : Journal of Chemical Reactivity and Synthesis

Soheil Sayyahi ¹ , Sedigheh Jahanbakhshi ² , Zahra Dehghani ³

1 - Chemistry Department, Mahshahr Branch, Islamic Azad University, Mahshahr 63519, Iran
2 - Chemistry Department, Omidieh Branch, Islamic Azad University, Omidieh, Iran
3 - Chemistry Department, Omidieh Branch, Islamic Azad University, Omidieh, Iran

تاریخ دریافت : 1395/03/09 تاریخ پذیرش : 1395/03/09 تاریخ انتشار : 1390/02/11

کلید واژه: Biginelli reaction, Multicomponent reactions, organoclay, 3, 4-Dihydropyrimidin-2(1H)-ones,

چکیده مقاله :

The reactive intermediate generated by the addition of tert-butyl and 1,1,3,3-tetramethyl butyl isocyanide and cyclohexyl isocyanide to dialkyl acetylenedicarboxylate was trapped by 3-hydroxy pyridine to produce highly functionalized 4H-chromenes in fairly good  yields