A New synthesis of functionalized imidazo[2,1-b][1,3]thiazines with thiohydantoins, isocyanides and dialkyl acetylenedicarboxylates

محورهای موضوعی : Journal of Chemical Reactivity and Synthesis

Pegah Mohagheghzadeh ¹ , Soheila Ghassamipoor ² , Mohammad Mehdi Ghanbari ³ , Elham Ahmadi ⁴

1 - Young Researchers and Elite Club, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
2 - Young Researchers and Elite Club, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
3 - Young Researchers and Elite Club, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran
4 - Young Researchers and Elite Club, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran

تاریخ دریافت : 1395/03/09 تاریخ پذیرش : 1395/03/09 تاریخ انتشار : 1390/02/11

کلید واژه: Thiohydantoin, Imidazo[2, 1-b][1, 3]thiazine, isocyanide, Acetylenedicarboxylate, Zwitterionic,

چکیده مقاله :

The reaction of stoichiometric amounts of dialkyl acetylenedicarboxylates with alkyl isocyanides and 5,5-diaryl thiohydantoins in toluene and catalytic amount of p-TSA afforded imidazo[2,1-b][1,3]thiazines in good overall yields