Calcium Chloride catalyzed Intramolecular Oxa Michael addition of 2’-Hydroxychalcone to Flavanone

محورهای موضوعی : Journal of Chemical Reactivity and Synthesis

Pramod Kulkarni ¹ (Department of Chemistry, Hutatma Rajguru Mahavidyalaya Rajgurunagar Pune 410505 (MS) India)

تاریخ دریافت : 1395/03/12 تاریخ پذیرش : 1395/03/12 تاریخ انتشار : 1391/02/12

کلید واژه: Calcium chloride, 2’-hydroxy chalcone, flavanone, intramoleclar, Oxa-michael reaction,

چکیده مقاله :

An efficient cyclization of 2’-hydroxychalcone to flavanone using calcium chloride as a catalyst was developed. The scope of the reaction was studied with substituted 2’-hydroxychalcone and these chalcones was converted into corresponding flavanone in good yield. The merits of this method are inexpensive and easily available catalyst, easy workup procedure, avoid use of toxic solvent