Effects of lifestyle activity modification on insulin resistance and pancreatic β-cells function in obese men with insulin resistance
محورهای موضوعی : Journal of Physical Activity and HormonesMohadeseh Nematollahzadeh mahani 1 , Jalil Ghasemian poor 2
1 - The General Department of Fars Province Education
2 - The General Department of Fars Province Education
کلید واژه: Insulin resistance, Obesity, Lifestyle activity modification, Pancreatic &beta, -cells function,
چکیده مقاله :
Introduction: Pancreatic β-cells function and insulin sensitivity resistance were impaired in type 2 diabetes. The effect of lifestyle activity modification (LAM) on these parameters is unclear. The aim of present study was to examine the effect of 8 weeks LAM on pancreatic β-cells function and insulin resistance in middle aged men with insulin resistance. Material & Methods: Sixteen obese and overweight middle aged men (age, 35-50 years) with insulin resistance participated in this study. The subjects were randomly assigned to LAM group (n=8) or control group (n=8). The subjects in LAM group walked 2 miles in 30 minutes on a treadmill on 4 days per week for 12 weeks according to the guidelines of the Centers for Disease Control and Prevention and American College of Sports Medicine. Results: The results indicated that fasting blood sugar, fasting insulin and insulin resistance index decreased and pancreatic β-cells function increased significantly after the intervention. Conclusion: In summary, it seems that LAM improves insulin resistance and pancreatic β-cells function in obese men with insulin resistance.
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