Design and Simulation of Novel Optofluidic ring resonator for Biomolecular Detection

محورهای موضوعی : Majlesi Journal of Telecommunication Devices

Keyvan Amini ¹ , Saman Amini ² , Hadi Veladi ³

1 - Tabriz university, Faculty of Electrical and Computer Engineering
2 -
3 -

تاریخ دریافت : 1396/03/08 تاریخ پذیرش : 1396/03/15 تاریخ انتشار : 1396/04/10

کلید واژه: Microfluidic, Optofluidic, OFRR, Ring resonator, PDMS, en, BRIS, Biomolecular Detection,

چکیده مقاله :

     In This study, a label-free detection method by using a novel Optofluidic ring resonator sensor (OFRR) structure is presented. Optofluidic is a developed young research subject suitable to create an appropriate cooperation between optics and fluidics. The combination of fluidic and optical methods achievable. by using the optofluidic methods makes it expedient to obtain an inventive type of sensors, which have been tried to have an ameliorate sensitivity, denseness and adaptivity.  OFRR is a recent detection method that integrates Optic and fluid technologies with low-limit and low-cost and small- sample volume detection sensitivity. The objective of this article is the detection of the tuberculosis by offering a unique and a novel useful structure that is able to fabricate. The material of the proposed structure is PDMA that is completely flexible polymer. The width of the waveguide, the waveguide length and width of the ring of the proposed structure respectively is 500nm, 250 nm, 1500 nm. Also, the inner radius of the resonator ring in 4700 nm. The simulation Result of proposed structure by Opti-FDTD software shown 649 nm/RIS for the slope of the sensitivity curve.

منابع و مأخذ:

[1] Testa, Genni, et al. "Integrated silicon optofluidic ring resonator." Applied Physics Letters 97.13 (2010): 131110.

[2] Testa, G., G. Persichetti, and R. Bernini. "Design and optimization of an optofluidic ring resonator based on liquid-core hybrid ARROWs." IEEE Photonics Journal 6.5 (2014): 1-14.

[3] Erickson, David, et al. "Nanofluidic tuning of photonic crystal circuits." Optics Letters 31.1 (2006): 59-61.

[4] Passaro, Davide, et al. "All-silica hollow-core microstructured Bragg fibers for biosensor application." IEEE Sensors Journal 8.7 (2008): 1280-1286.

[5] Webb, Andrew S., et al. "Suspended-core holey fiber for evanescent-field sensing." Optical Engineering 46.1 (2007): 010503-010503.

[6] Coscelli, Enrico, et al. "Toward a highly specific DNA biosensor: PNA-modified suspended-core photonic crystal fibers." IEEE Journal of Selected Topics in Quantum Electronics 16.4 (2010): 967-972.

[7] Almeida, Vilson R., et al. "Guiding and confining light in void nanostructure." Optics letters 29.11 (2004): 1209-1211.

[8] Xu, Qianfan, et al. "Experimental demonstration of guiding and confining light in nanometer-size low-refractive-index material." Optics letters 29.14 (2004): 1626-1628.

[9] Testa, Genni, and Romeo Bernini. "Slot and layer-slot waveguide in the visible spectrum." Journal of Lightwave Technology 29.19 (2011): 2979-2984.

[10] Wolfe, Daniel B., et al. "Dynamic control of liquid-core/liquid-cladding optical waveguides." Proceedings of the National Academy of Sciences of the United States of America 101.34 (2004): 12434-12438.

[11] Bernini, R., et al. "Liquid-core/liquid-cladding integrated silicon ARROW waveguides." Optics Communications 281.8 (2008): 2062-2066.

[12] Takiguchi, Hiromi, et al. "Liquid/liquid optical waveguides using sheath flow as a new tool for liquid/liquid interfacial measurements." Applied spectroscopy 57.8 (2003): 1039-1041.

[13] Hairer, Gabriel, and Michael J. Vellekoop. "An integrated flow-cell for full sample stream control." Microfluidics and nanofluidics 7.5 (2009): 647.

[14] Abgrall, P., and A. M. Gue. "Lab-on-chip technologies: making a microfluidic network and coupling it into a complete microsystem—a review." Journal of Micromechanics and Microengineering 17.5 (2007): R15.

[15] Lee, S. J., and S. Y. Lee. "Micro total analysis system (μ-TAS) in biotechnology." Applied microbiology and biotechnology 64.3 (2004): 289-299.

[16] Zheng, Yi, et al. "Recent advances in microfluidic techniques for single-cell biophysical characterization." Lab on a Chip 13.13 (2013): 2464-2483.

[17] Persichetti, Gianluca, Genni Testa, and Romeo Bernini. "High sensitivity UV fluorescence spectroscopy based on an optofluidic jet waveguide." Optics express 21.20 (2013): 24219-24230.

[18] Sun, Yuze, and Xudong Fan. "Optical ring resonators for biochemical and chemical sensing." Analytical and bioanalytical chemistry 399.1 (2011): 205-211.

[19] Tanyeri, Melikhan, and Ian M. Kennedy. "Detecting single bacterial cells through optical resonances in microdroplets." Sensor letters 6.2 (2008): 326-329.

[20] Poli, Federica, Annamaria Cucinotta, and Stefano Selleri. Photonic crystal fibers: properties and applications. Vol. 102. Springer Science & Business Media, 2007.