One-pot Synthesis of Polysubstituted Indolizine Derivatives

محورهای موضوعی : پلیمر

Mohammad Piltan ¹ , Seyed Amir Zarei ² , Hassan Saydi ³ , Ashraf Sadat Shahvelayati ⁴

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تاریخ دریافت : 1395/05/01 تاریخ پذیرش : 1395/05/01 تاریخ انتشار : 1395/04/11

کلید واژه:

چکیده مقاله :

An efficient approach to the synthesis of 1,2,3-trisubstituted indolizines is described via one-pot reactions of pyridine and dialkyl acetylendicarboxylate in the presence of ethyl 2-chloroacetoacetate in MeOH at room temperature. The corresponding 1, 2, 3-trisubstituted indolizines may be useful building blocks for the construction of complex indolizine derivatives.