Efficient one-pot synthesis and characterization of 13-Acetyl-9-methyl-11-oxo-8-oxa-10,12-diazatricyclo [7.3.1.0^2,7] trideca-2,4,6-triene

محورهای موضوعی : Journal of Physical & Theoretical Chemistry

Hojatollah Salehi ¹ , Mohammad Rabbani ² , Qian-Rong Li ³ , Qing-xiang Guo ⁴

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تاریخ دریافت : 1394/02/07 تاریخ پذیرش : 1394/02/07 تاریخ انتشار : 1384/02/11

کلید واژه: Oxygen-bridged dihydropyrimidi, Intramolecular Michael-additio, One-pot-solvent-free synthesis, NMR and EL_TOFMS,

چکیده مقاله :

An efficient and environmentally friendly procedure for one-pot synthesis of 13-acetyl-9-methyl-11-ox-8-oxa-10,12-diazatricyclo [7.3.1. ] trideca-2,4,6-triene from salicylaldehyde, acetylaceton and urea via Biginelli condensation and intramolecular Michael-addition by using magnesium bromide as an expensive and easily available catalyst under solvent-free condition is desired. The structural elucidation of the product is also described by -and -NMR spectra and the detailed fragmentation routs of EI-TOFMS