The chaperone ability comparison of norma II-casein and modified d-casein upon interaction with lysozinie
محورهای موضوعی : Journal of Physical & Theoretical Chemistry
H. Rajabzadeh
1
(-)
D. Nourouzian
2
(-)
K. Zare
3
(-)
F. Mollaamin
4
(-)
کلید واژه: Modified ffeasein, Lysoiyme: Hydrophobicity, Disaggregatiorr, Woodward's re,
چکیده مقاله :
Diminishing protein aggregation by chaperone is very important factor in medicine and industry. In this paper, itis induced the chaperone ability for 0-casein upon modification of its acidic residues by Woodward reagentK(WRK) and examined on lysozyme as a target protein at pH 7.2 and outlined the mechanism for chaperoneability of modified system by UV-Vis and fluorescence spectroscopy and theoretical calculation methods.
