Optical Properties of Coupled Gold Nanoparticles: A Numerical Study for Photothermal Applications
محورهای موضوعی : Photonics in Cancer TreatmentRaha Rasouli Sghai 1 , Vahid Rajabpour 2
1 - Faculty of Electrical and Computer Engineering, University of Tabriz, Tabriz, Iran
2 - Faculty of Electrical and Computer Engineering, University of Tabriz, Tabriz, Iran
کلید واژه: Photothermal Therapy, Localized Surface Plasmon Resonance, Gold Nanodimers, Nanorod, Nanopyramid, Nanocube, Field Enhancement,
چکیده مقاله :
Photothermal therapy (PTT) using plasmonic nanoparticles, particularly gold, is a promising method for cancer cell ablation. However, optimizing the morphology and size of nanoparticles for efficient light absorption and heat conversion remains challenging. Plasmonic metamolecules, like gold nanodimers, demonstrate significant localized field enhancement and strong infrared light absorption. In this study, we investigate gold nanoparticles with spherical, rod, pyramid, and cubic morphologies in both monomeric and dimeric forms. For dimer structures, side-by-side and end-to-end couplings were considered. Our analysis includes parameters such as absorption cross-section, photothermal conversion efficiency (PCE), and field enhancement to compare the optical properties of these nanostructures within the first biological window. Our findings suggest that gold nanopyramids, with their suitable PCE, intermediate peak wavelength spacing in side-by-side and end-to-end dimers, and significant local field enhancement, are more controllable candidates for photothermal applications.
Photothermal therapy (PTT) using plasmonic nanoparticles, particularly gold, is a promising method for cancer cell ablation. However, optimizing the morphology and size of nanoparticles for efficient light absorption and heat conversion remains challenging. Plasmonic metamolecules, like gold nanodimers, demonstrate significant localized field enhancement and strong infrared light absorption. In this study, we investigate gold nanoparticles with spherical, rod, pyramid, and cubic morphologies in both monomeric and dimeric forms. For dimer structures, side-by-side and end-to-end couplings were considered. Our analysis includes parameters such as absorption cross-section, photothermal conversion efficiency (PCE), and field enhancement to compare the optical properties of these nanostructures within the first biological window. Our findings suggest that gold nanopyramids, with their suitable PCE, intermediate peak wavelength spacing in side-by-side and end-to-end dimers, and significant local field enhancement, are more controllable candidates for photothermal applications.
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