Synthesis, Characterization, Antioxidant, Anti-fungal, and Antibacterial Activities of a New 1-Isopropyl-3,5-diphenyl-1,3,5-triazinane
محورهای موضوعی :Soria Zouchoune 1 , Leila Lefrada 2 , Nassiba Chafaa 3 , Latifa khattabi 4 , Ahcene Bouchemma 5
1 - Laboratory of Analytical Sciences Materials and Environment LSAME, Faculty of Exact Sciences and Sciences of Nature and Life, Larbi ben M'Hidi University, 04000 Oum El Bouaghi, Algeria
2 - Laboratory of Analytical Sciences Materials and Environment LSAME, Faculty of Exact Sciences and Sciences of Nature and Life, Larbi ben M'Hidi University, 04000 Oum El Bouaghi, Algeria
3 - Laboratory of Natural Substances, Bioactives Molecules and Biotechnological Application, Faculty of Exact Sciences and Sciences of Nature and Life, Larbi ben M'Hidi University, 04000 Oum El Bouaghi, Algeria
4 - Centre de Recherche en Biotechnologie, Ali Mendjli Nouvelle Ville UV 03, BP E73 Constantine, Algeria
5 - Laboratory of Applied Chemistry and Materials Technology LCATM, Faculty of Exact Sciences and Sciences of Nature and Life, Larbi ben M'Hidi University, 04000 Oum El Bouaghi, Algeria
کلید واژه: Synthesis, Antioxidant, Antimicrobial, Antifungal, 1, 3, 5-triazinane,
چکیده مقاله :
In this work, we present the green synthesis of a novel of 1-isopropyl-3,5-diphenyl-1,3,5-triazinane, It is made without a solvent, The multicomponent condensation reaction between isopropylamine, aniline, and formaline. The structures of this compound have been characterized by TLC, UV, IR, 1H NMR and 13C NMR. The antioxidant activity showed good antioxidant activity in ABTS, Phenanthroline. The antimicrobial activity of this novel molecule was tested against four bacterial and fungal strains using the disk diffusion method. The obtained results exhibited a high level of antibacterial and antifungal activity.
In this work, we present the green synthesis of a novel of 1-isopropyl-3,5-diphenyl-1,3,5-triazinane, It is made without a solvent, The multicomponent condensation reaction between isopropylamine, aniline, and formaline. The structures of this compound have been characterized by TLC, UV, IR, 1H NMR and 13C NMR. The antioxidant activity showed good antioxidant activity in ABTS, Phenanthroline. The antimicrobial activity of this novel molecule was tested against four bacterial and fungal strains using the disk diffusion method. The obtained results exhibited a high level of antibacterial and antifungal activity.
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