مروری بر اثرات درمانی گونه‌های گیاه Salvia (تیره نعناعیان) در ایران

محورهای موضوعی : فصلنامه زیست شناسی جانوری

ویدا حجتی ¹

1 - گروه زیست شناسی دانشکده علوم پایه دانشگاه آزاد اسلامی واحد دامغان

تاریخ دریافت : 1401/06/14 تاریخ پذیرش : 1401/09/12 تاریخ انتشار : 1402/03/01

کلید واژه: گیاه دارویی, salvia, آنتی‌اکسیدانت, مریم‌گلی, نعناعیان,

چکیده مقاله :

گونه های جنس Salvia از تیره ی نعناعیان (Labiatae) در ایران تحت عنوان مریم گلی شناخته شده و بخاطر دارا بودن خواص دارویی و درمانی از قدیم مورد استفاده قرار می گرفته اند. 58 گونه از این جنس در کشور شناسایی شده که تعدادی از آنها بومی ایران می باشند. با توجه به مطالعات متعددی که روی این گیاه انجام شده، هدف از این مطالعه، مروری بر متون علمی با موضوعیت اثرات دارویی و درمانی گونه های گیاه سالویا در حوزه های زیست شناسی و پزشکی در دو دهه ی اخیر می باشد. برای این پژوهش مروری، با استفاده از کلید واژه ها ی مریم گلی و Salvia تعداد 100 رفرنس مشتمل بر یک کتاب پایان نامه (به راهنمایی نویسنده) و 99 مقاله (نشریات و کنگره ها) از محققان ایرانی از طریق پایگاه استنادی علوم جهان اسلام (ISC)، اسکوپوس و مرکز اطلاعات علمی جهاد دانشگاهی (SID) بررسی شده است. مطالعات صورت گرفته بر روی ترکیبات و مواد موثره ، خواص آنتی اکسیدانی، ضدالتهابی، ضدمیکروبی، ضددردی و دیگر کاربردهای مختلف گیاه بوده است. گیاه سالویا در درمان تومورها، دیابت، آلزایمر، اضطراب، افسردگی، ایسکمی، ترمیم زخم، بیماری های کبدی، کلیوی، مقاربتی، تیروئیدی، دهان و لثه، قاعدگی، گرگرفتگی یائسگی استفاده شده و تاثیرات بسیار مفید و مثبت آن از نظر علمی ثابت شده است. گونه های سالویا به دلیل دارا بودن ترکیبات آنتی اکسیدانی و ضدالتهابی نقش عمده ای در پیشگری و درمان عوارض ناشی از استرس های اکسیداتیو و بسیاری از بیماری ها دارند. همچنین به دلیل ارزانی و عوارض جانبی اندک جزو درمان های بی خطر محسوب می شوند.

چکیده انگلیسی:

The species of the Salvia genus from the mint family (Labiatae) are known as Maryam-Goli and have been used since ancient times due to their medicinal and therapeutic properties. 58 species of this genus have been identified in the country, some of which are native to Iran. According to the many studies that have been done on this plant, the aim of this study is to review the scientific literature on the medicinal and therapeutic effects of salvia species in the fields of biology and medicine in recent two decades. It is recent. For this review research, using the keywords Sage and Salvia, 100 references including one thesis book (under the guidance of the author) and 99 articles (publications and congresses) from Iranian researchers through The databases of Islamic World Science Citation Center (ISC), Scopus and Scientific Information Database (SID) have been prepared and reviewed. Studies have been conducted on compounds and effective substances, antioxidant, anti-inflammatory, antimicrobial, analgesic and other different uses of the plant. Salvia plant has been used in the treatment of tumors, diabetes, Alzheimer's, anxiety, depression, ischemia, wound healing, liver, kidney, sexual, thyroid, mouth and gum diseases, menstruation, menopausal hot flashes, and its very useful and positive effects are scientifically proven. It has been proved. Due to the presence of antioxidant and anti-inflammatory compounds, Salvia species play a major role in the prevention and treatment of complications caused by oxidative stress and many diseases. Also, due to their cheapness and few side effects, they are considered safe treatments.

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94. Shirdel R., Soheili S., Parsian H. 2021.The effect of aerobic exercise combined with Salvia officinalis extract on the changes of premenstrual syndrome symptoms in inactive women. Journal of Sport Physiology and Management Investigations, 13(2):177-185.


95. Shojaei Borjoei M.H., Norouzi S., Barnous P., Mokhtari K., Asadzadeh A. Comparison of inhibition of active compounds of sage with antidiabetic drugs voglibose and miglitol in suppressing alphaglucosidase enzyme by in silico method. Iranian Journal of Diabetes and Metabolism, 22(3):145-154.


96. Taheri S., Shajiee H., Ashabi G., Khalifeh S. 2022. Evaluating the effect of Salvia macilenta extract on CREB protein level and acetylcholine esterase activity in the brain of Alzheimer’s disease in male rats. Journal of Animal Biology, 14(3):235-245.


97. Tavassoli A., Esmaeili A., Akbarzadeh M., Ebrahimzadeh M.A. Investigating the chemical composition of the essential oil of Salvia glutinosa L. and its application in medicine. National Conference of Medicinal Plants.


98. Tehranipour M., Gadamyari T. Investigating the effect of the alcoholic extract of Salvia staminea leaves on the degeneration of spinal cord motoneurons after sciatic nerve compression in rats. Journal of Animal Physiology and Development, 4(1):59-65.


99. Yousefi M., Taghipour S., Arefkhah N., Rahimian R., Davoudian A., Rafieiyan M., Yousefi Darani H. The effect of hydroalcoholic extracts of mint and sage on Trichomonas vaginalis in laboratory conditions. Journal of Isfahan University of Medical Sciences, 31(240):811-818.


100.  Zarban A., Malekaneh M., Hasanpour M., Najari M.T., Abad M. Evaluation of antioxidant properties of 28 Iranian medicinal plants.Journal of Birjand University of Medical Sciences, 11(1):13-15.