Effects of High Dietary Levels of Selenium and Copper on Growth Performance, Selected Blood Biochemical Parameters and Antibody Production Against Newcastle Disease Vaccine Virus in Broiler Chickens
محورهای موضوعی : Camelترکی م. 1 , م. حبیبیان 2 , ط. رستمی 3 , آ. مرادی 4
1 - Department of Animal Science, College of Agriculture and Natural Resources, Razi University, Kermanshah, Iran
2 - Department of Animal Science, Faculty of Agriculture, University of Kurdistan, Sanandaj, Iran
3 - Department of Animal Science, College of Agriculture and Natural Resources, Razi University, Kermanshah, Iran
4 - Department of Animal Science, College of Agriculture and Natural Resources, Razi University, Kermanshah, Iran
کلید واژه: Performance, Copper, blood parameters, broilers, Newcastle disease, selenium,
چکیده مقاله :
An experiment was conducted to evaluate the effects of high dietary levels of selenium (as sodium selenite) and copper (as copper sulphate) on growth performance, serum biochemical parameters and antibody production against Newcastle disease vaccine (NDV) virus in broiler chickens. A total of 160 Ross 308 unsexed day old broiler chickens were randomly allocated into four treatment groups (n=40 per group) each comprising four replicates (n=10 per replicate). Group 1 was served as control and the chickens in this group were fed a standard diet without any selenium or copper supplementation. Chickens in Group 2 received a diet with selenium supplementation at the rate of 1 mg/kg of feed; Group 3 received a diet with copper supplementation at the rate of 200 mg/kg of feed; Group 4 received a diet supplemented with a combination of 1 mg/kg selenium and 200 mg/kg copper. Combined supplementation of selenium and copper decreased feed intake and body weight gain and increased feed conversion ratio (P<0.05). These effects were not observed when selenium or copper was supplemented alone (P>0.05). Serum uric acid and triglycerides concentrations decreased (P<0.05) and tended to be increased (P=0.11), respectively, by feeding copper and selenium. Moreover, serum albumin concentration was significantly increased in chickens given copper supplementation alone (P<0.05), but not in those supplemented with copper and selenium (P>0.05). Dietary treatments had no effects on antibody titres against NDV at day 28 of age (P>0.05); antibody titres against NDV, however, decreased at day 42 of age in broilers receiving a combination of copper and selenium (P<0.05). The results clearly indicate a negative interaction between the usage of sodium selenite and copper sulphate on growth performance in broiler chickens. More studies should be performed to clarify the action modes of such effects.
یک آزمایش جهت ارزیابی اثرات تغذیه سطوح بالای سلنیوم (به شکل سلنیت سدیم) و مس (به شکل سولفات مس) بر عملکرد رشد، پارامترهای بیوشیمیایی سرم و تولید آنتی بادی علیه ویروس بیماری نیوکاسل در جوجههای گوشتی انجام شد. مجموع 160 جوجه گوشتی یکروزه راس 308 از مخلوط دو جنس به صورت تصادفی بین چهار گروه تیماری (40 جوجه در هر گروه) و هر کدام شامل چهار تکرار (10 جوجه به ازای هر تکرار) تقسیم شدند. گروه 1 به عنوان شاهد در نظر گرفته شد و جوجهها در این گروه یک جیره استاندارد بدون مکمل سلنیوم و مس را دریافت کردند. جوجهها در گروه 2 یک جیره حاوی مکمل سلنیوم به میزان 1 میلیگرم/کیلوگرم، در گروه 3 یک جیره حاوی مکمل مس به میزان 200 میلیگرم بر کیلوگرم و در گروه 4 یک جیره مکمل شده با 1 میلیگرم/کیلوگرم سلنیوم و 200 میلیگرم/کیلوگرم مس را دریافت کردند. استفاده هم زمان از مکملهای سلنیوم و مس مصرف خوراک و وزن بدن را کاهش و ضریب تبدیل خوراک را افزایش داد (05/0P<). این اثرات هنگام استفاده از سلنیوم یا مس به تنهایی مشاهده نشد (05/0P>). غلظت سرمی اسید اوریک با تغذیه مس کاهش یافت (05/0P<) و غلظت تریگلیسریدها با تغذیه سلنیوم تمایل به افزایش داشت (11/0P=). علاوه بر این، غلظت سرمی آلبومین به طور معنی داری در جوجههای دریافت کننده مکمل مس افزایش یافت (05/0P<)، اما این اثرات با استفاده هم زمان از مس و سلنیوم دیده نشد (05/0P>). تیتر آنتیبادی علیه ویروس نیوکاسل در 28 روزگی تحت تأثیر گروههای آزمایشی قرار نگرفت (05/0P>)، اما در 42 روزگی در گروه دریافت کننده ترکیب سلنیوم و مس کاهش یافت (05/0P<). این نتایج به روشنی بیانگر برهمکنش منفی بین استفاده از سلنیت سدیم و سولفات مس بر عملکرد رشد جوجههای گوشتی است. لازم است مطالعات بیشتری جهت مشخص کردن سازوکار این اثرات انجام شود.
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