Genome Wide Association Studies, Next Generation Sequencing and Their Application in Animal Breeding and Genetics: A Review
محورهای موضوعی : Camelح. خانزاده 1 , ن. قوی حسین-زاده 2 , ش. قوتی 3
1 - Department of Animal Science, Faculty of Agricultural Science, University of Guilan, Rasht, Iran
2 - Department of Animal Science, Faculty of Agricultural Science, University of Guilan, Rasht, Iran
3 - Department of Animal Science, Faculty of Agricultural Science, University of Guilan, Rasht, Iran
کلید واژه: Livestock, genome wide association studies, genomics, next generation sequenc-ing,
چکیده مقاله :
Recently genetic studies have been revolutionized by next generation sequencing (NGS) technology, and it is expected that the use of this technology will largely eliminate defects in the methods of association studies. The NGS technology is becoming the premier tool in genetics. However, at the moment the use of this method is limited especially in the livestock due to high cost and computational problems. But it is expected that the development of sequencing and computing technologies and reducing the cost will have significant impacts on the livestock health and production. This study reviews the literature on genetic association studies, NGS technologies and their application in animal breeding.
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