Facile one-pot multicomponent synthesis of 2-amino-6-(2-oxo-2H-chromen- 3-yl)-4-arylpyridine-3-carbonitriles using Brønsted acidic ionic liquid as catalyst under solvent-free conditions

محورهای موضوعی : Iranian Journal of Catalysis

Janardhan Banothu ¹ (Department of Chemistry, National Institute of Technology, Warangal, A.P., India.)
Rajitha Bavantula ² (Department of Chemistry, National Institute of Technology, Warangal, A.P., India.)
Peter Crooks ³ (Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.)

تاریخ دریافت : 1392/01/11 تاریخ پذیرش : 1392/02/23 تاریخ انتشار : 1391/12/11

کلید واژه: 2-Amino pyridine-3-carbinitrile, Multicomponent condensation, 3-Acetyl-2H-chromen-2-ones, (4-Sulfobutyl)tris-(4-sulfophenyl)phosphonium hydrogen sulfate,

چکیده مقاله :

A series of 2-amino pyridine-3-carbinitrile derivatives incorporated coumarin moiety has developed via multicomponent condensation of 3-acetyl-2H-chromen-2-one, arylaldehydes, malononitrile and ammonium acetate utilizing Brønsted acidic ionic liquid, (4-sulfobutyl)tris(4-sulfophenyl)phosphonium hydrogen sulfate as catalyst under solvent-free conditions. Good yields, short reaction times, straight forward workup, reusability of the ionic liquid and green conditions are the most obvious advantages of this methodology.

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