A novel three-component reactions of 4-hydroxycumarine for the synthesis of oxazine derivatives in water
محورهای موضوعی : Iranian Journal of Organic ChemistrySeyyed Jalal Shams Najafi 1 , Maryam Ghazvini 2 , Atefeh Navabi 3
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کلید واژه: 1, Three-component reaction, isocyanide, 2-hydroxyacetophenone, 3-benzoxazine, Isoquinoline,
چکیده مقاله :
A simple and proficient method for the synthesis of 1,3-benzoxazine derivatives via three-component reaction of isocyanide and isoquinoline with 2-naphthol in water in the presence of piperidine at 70oC is reported.