Green synthesis of morpholine-2-thione by multicomponent reaction of aziridines
محورهای موضوعی : Iranian Journal of Organic Chemistry
Narges Ghasemi
1
()
Samaneh sadat Sharifi
2
()
کلید واژه: multi component reaction, Aziridin, Carbone disulfide, Nitro methane,
چکیده مقاله :
A series of substituted morpholine-2-thione derivatives were synthesized via one-pot multicomponent reactions of nitromethane, carbon disulfide and aziridine in the presence of Et3N under solvent-free conditions. Particularly valuable features of this method include high yields of products, broad substrate scope, short reaction time and straightforward procedure.