Catalyst free synthesis of pyrrole derivatives using multicomponent reactions

محورهای موضوعی : Iranian Journal of Organic Chemistry

Samanehsadat Sharifi ¹ , Narjes Haeizadeh ²

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تاریخ دریافت : 1402/05/23 تاریخ پذیرش : 1402/05/23 تاریخ انتشار : 1402/02/11

کلید واژه: Three-component reaction, Primary Amines, Pyrrole, green chemistry, N-formylmorpholine,

چکیده مقاله :

A convenient and efficient procedure for the synthesis of substituted pyrroles has been reported based on three component reactions of primary amines and activated acetylenic compounds in the presence of N-formylmorpholine as a green solvent. The above synthetic procedure offers rapid access to novel and diversely substituted pyrrole derivatives.