A Simple and one-pot synthesis of imintriazole derivatives under Solvent-free conditions

محورهای موضوعی : Iranian Journal of Organic Chemistry

Narges Ghasemi ¹ , Parvaneh Firoozi Khanghah ² , Mahboubeh Ghasemian Dazmiri ³

1 -
2 -
3 -

تاریخ دریافت : 1401/12/09 تاریخ پذیرش : 1401/12/09 تاریخ انتشار : 1401/11/12

کلید واژه: Solvent-free, One-pot reaction, Acid chlorides, Hydrazonoyl chloride, 3-amino-2-butanone,

چکیده مقاله :

An efficient synthesis of iminetriazole derivatives is described via an one-pot reaction between acid chlorides, 3-amino-2-butanone, primary amines and hydrazonoyl chloride under solvent-free conditions at room temperature in good yields. Also, the antimicrobial activity of some synthesized compounds proved by employing the disk diffusion test on Gram-positive and Gram-negative bacteria. This procedure has some benefits such as short reaction time, product with excellent yields, simple catalyst and products separation.