Catalyst-free synthesis of aminothiazole derivatives in water

محورهای موضوعی : Iranian Journal of Organic Chemistry

Mahboubeh Ghasemian Dazmiri ¹ , Narges Ghasemi ² , Annataj Noushin ³

1 -
2 -
3 -

تاریخ دریافت : 1401/09/30 تاریخ پذیرش : 1401/09/30 تاریخ انتشار : 1401/05/10

کلید واژه: Primary Amines, aminothiazole, Phosphonate, Phosphites, Activated acetylenic compound, Benzoylisothiocyanates,

چکیده مقاله :

Functionalized aminothiazole are generated from the reaction of dimethyl acetylenedicarboxylate, benzoylisothiocyanates, primary amines, hydrazonoyl chloride and triphenylphosphine in water. Particularly valuable features of this method include high yields of products, broad substrate scope, short reaction time and straightforward procedure.