Green synthesis of oxazole triazole derivatives: Application of Fe3O4@MWCNT MNCs

محورهای موضوعی : Iranian Journal of Organic Chemistry

Samaneh Sadat Sharifi ¹ , Seyyed Jalal Shams Najafi ² , Majid Ghazanfarpour ³

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تاریخ دریافت : 1401/09/30 تاریخ پذیرش : 1401/09/30 تاریخ انتشار : 1401/05/10

کلید واژه: Ammonium thiocyanate, Fe3O4@MWCNT MNCs, 1, 3-oxazole, Isothiocyanates, Alkyl (aryl) isothiocyanates,

چکیده مقاله :

1,3-oxazole derivatives were prepared via multicomponent reaction of α-bromo ketones, acid chlorides andammonium thiocyanate in the presence of catalytic amount of Fe3O4@MWCNT MNCs in water at 50oC in good yields. Also, the reaction of alkyl (aryl) isothiocyanates and -bromo ketones in the presence of catalytic amount of Fe3O4 MNPs in water at 50oC are investigated. The catalyst was reused five times with minor decrease in its catalytic activity. In addition, high yields, easy procedure, easy separation of catalyst from the mixture of reactions are the advantages of these reactions.