Journal of the Iranian Chemical Research: 5 (4)

Open Access Article

1 - Preparation and molecular weight determination of soya-beans and benniseed oil-modified alkyd resins
Adeniyi S. Ogunlaja Olufunmilayo Abiona

Alkyd resins were prepared into four different sets by varying the percentage concentrationof the glycerol content. Various properties such as the viscosity, Surface drying time, solubilityand color of the alkyd resins were evaluated for the various sets. The alkyd resi More

Alkyd resins were prepared into four different sets by varying the percentage concentrationof the glycerol content. Various properties such as the viscosity, Surface drying time, solubilityand color of the alkyd resins were evaluated for the various sets. The alkyd resin with the highestglycerol content was the most viscous, brownish in color and having the highest molecularweight this is due to the ratio 1:3 oil to glycerol content. Manuscript profile

Open Access Article

2 - Conformational Study of some novel Methoxy Half-Analogues of Michler’s Ketone by NMR
Naghi Saadatjou Geoffrey Hallas

One series of half-analogues of Michler’s ketone containing one or more terminal methoxysubstituents with variable tertiary amino groups have been used in this study. NMR spectralresults for the parent ketones confirm earlier findings that ortho proton shifts are More

One series of half-analogues of Michler’s ketone containing one or more terminal methoxysubstituents with variable tertiary amino groups have been used in this study. NMR spectralresults for the parent ketones confirm earlier findings that ortho proton shifts are apparentlyindependent from steric effects in derivatives of Michler’s ketone because the ring current andcarbonyl-induced shifts are self-canceling. Manuscript profile

Open Access Article

3 - Silica sulfuric acid mediated protection of carbonyl groups as 2,4- dinitrophenylhydrazone
Mehdi Fallah-Mehrjardi Ali Reza Kiasat

Silica sulfuric acid is employed as solid acid catalyst for the clean and less hazardousprotection of carbonyl compounds as 2,4-dinitrophenylhydrazone under solvent-free conditions.

Silica sulfuric acid is employed as solid acid catalyst for the clean and less hazardousprotection of carbonyl compounds as 2,4-dinitrophenylhydrazone under solvent-free conditions. Manuscript profile

Open Access Article

4 - Potentiometeric study of protonation and complex formation of some amino acids with Zn (II) , Co(II) and Ni (II) in aqueous solution
Mohammad Mazloum-Ardakani Sharam Lotfi Jahan B. Ghasemi

The stability constants and complexation reaction between L-glutamine, L-arginine andglycine with Zn (II) , Co (II) and Ni (II) were studied potentiometrically in aqueous solution at25° C and μ=0.1 M KNO3. The overall stability constants log β´s of all More

The stability constants and complexation reaction between L-glutamine, L-arginine andglycine with Zn (II) , Co (II) and Ni (II) were studied potentiometrically in aqueous solution at25° C and μ=0.1 M KNO3. The overall stability constants log β´s of all species are obtained bycomputer refinement of pH-volume data using BEST computer program. Several models weretested and the lowest δFIT, the best one is accepted. The main species in binary complexes MHL,ML, ML2, MLOH, ML(OH)2 and for ternary complexes are ML1L2, ML1L2H, ML1L2OH,ML1L2(OH)2. The order found for the resulting stability constants vary as Co (II) < Ni (II) <Zn(II). The concentration distribution diagram was obtained with the program SPEPLOT. Manuscript profile

Open Access Article

5 - Thermodynamic, spectral and antimicrobial activity of inclusion complexes of acridone and its oxime with β-cyclodextrin
Swapna Sankar Nayak Sunakar Panda

One of the methods to enhance bio-accessibility of drugs like Acridone and its oxime is toform inclusion complexes with β-cyclodextrin. The formation of such complexes has beenconfirmed by changes in spectral characteristics and melting point data. The aqueous phas More

One of the methods to enhance bio-accessibility of drugs like Acridone and its oxime is toform inclusion complexes with β-cyclodextrin. The formation of such complexes has beenconfirmed by changes in spectral characteristics and melting point data. The aqueous phasesolubility studies reveal 1:1 stoichiometry between the compound and, β-cyclodextrin. The studyof thermodynamic parameters like ΔG, ΔH, ΔS indicates the inclusion complex formation to beexothermic and spontaneous. The study of antimicrobial activity of these compounds indicatesthat the microbes like E. coli and P. aeruginosa are susceptible and the susceptibility increasessignificantly after formation of inclusion complex. Manuscript profile

Open Access Article

6 - Solution state studies on thermodynamic parameters and complexation behavior of inner transition metal ions with creatinine in aqueous and mixed equilibria
Sangita Sharma Ashish Patel Jasmin Bhalodia Jayesh Ramani

The determination of formation constants of binary inner transition metal complexes where M=Y(III) or La(III) or Ce(III) or Pr(III) or Nd(III) or Sm (III) or Gd (III) or Dy (III) or Th(IV) andL = Creatinine have been carried out using Irving–Rossotti titration tec More

The determination of formation constants of binary inner transition metal complexes where M=Y(III) or La(III) or Ce(III) or Pr(III) or Nd(III) or Sm (III) or Gd (III) or Dy (III) or Th(IV) andL = Creatinine have been carried out using Irving–Rossotti titration technique in aqueous mediaat different temperatures and at ionic strength. To understand more about the nature ofequilibrium involving inner transition metals with Creatinine, the effect of dielectric constants onthe stability of these complexes at different percentage of solvent variation and at differentsolvent systems has been studied. The formation constant (logβn) have been calculated on IBMcomputer using BEST Program. Thermodynamic parameters (ΔG, ΔH and ΔS) are alsoevaluated, negative ΔG, ΔH and ΔS values indicate that complex formation is favorable atordinary temperatures. Species distribution curves of complexes have been plotted as function ofpH using Fortran IV program SPE PLOT to visualize the equilibria systems in pH range of 2-8pH. The order of stability for metals is Y < La < Ce < Pr < Nd < Sm < Gd < Dy < Th. This ordercan be explained on the basis of basicity of ligand, protonation of ligand, electronicconfiguration of metal ions, size and ionic potential of tripositive ion, charge/size ratio of metalions and species distribution diagrams. Manuscript profile

Open Access Article

7 - Biologically vital metal-based antimicrobial active mixed ligand complexes: synthesis, characterization, DNA binding and cleavage studies
Natarajan Raman Ramaraj Jeyamurugan Arumhgam Sakthivel Rajendran Antony

Few novel cobalt(II) and copper(II) complexes [M(fmp)3]Cl2, [M(fmp)(bpy)2]Cl2,[M(fmp)(phen)2]Cl2 and [M(fmp)(phen)(bpy)]Cl2 (fmp = 3-furan-2-ylmethylene-pentane-2,4-dione, phen = 1,10-phenanthroline, bpy = 2,2'-bipyridine) have been synthesized andcharacterized by eleme More

Few novel cobalt(II) and copper(II) complexes [M(fmp)3]Cl2, [M(fmp)(bpy)2]Cl2,[M(fmp)(phen)2]Cl2 and [M(fmp)(phen)(bpy)]Cl2 (fmp = 3-furan-2-ylmethylene-pentane-2,4-dione, phen = 1,10-phenanthroline, bpy = 2,2'-bipyridine) have been synthesized andcharacterized by elemental analyses, molar conductance, magnetic susceptibility measurements,IR, electronic, EPR, mass spectra and cyclic voltammetric studies. The synthesized complexesare found to be monomeric and electrolytic nature. The UV-Vis., magnetic susceptibility andEPR spectral data of the complexes suggest a distorted octahedral geometry for Cu(II)complexes and octahedral geometry for Co(II) complexes around the central metal ion. The CVprofile of the complexes shows a quasi-reversible peak which indicates that the metal-ligandlinkage is more covalent in nature. Spectroscopic and viscosity measurements prove that the[M(fmp)(phen)2]Cl2 complexes bind more efficiently with DNA than other complexes throughintercalative mode. The difference of peak potential and electrochemical parameters betweenfree and DNA-bound complexes shows the formation of an electrochemical active complexbetween synthesized complexes and DNA. All the complexes cleave the Supercoiled pUC19DNA in vitro under the presence of reducing agent (3-mercaptopropionic acid). The in vitroantimicrobial activities of the compounds have been tested against the bacterial and fungalstrains using the disc diffusion method. The minimum inhibitory concentration (MIC) valuesagainst the growth of microorganisms are much larger for metal chelates than the individualligands. Manuscript profile

Open Access Article

8 - Study of protonation equilibrium of lorazepam by potentiometry and multiwavelengths spectrophotometry
Ateesa Yazdanipour

The acid-base equilibrium of lorazepam was studied by means of potentiometry andmultiwavelengths spectrophotometry. The stoichiometric equilibrium constants were determinedat 25 °C and constant ionic strength 0.1 mol L-1 (NaCl). The acidity constants pK1=1.58&plusmn More

The acid-base equilibrium of lorazepam was studied by means of potentiometry andmultiwavelengths spectrophotometry. The stoichiometric equilibrium constants were determinedat 25 °C and constant ionic strength 0.1 mol L-1 (NaCl). The acidity constants pK1=1.58±0.05and pK2=11.67±0.07 were found by potentiometry, and pK1=1.54±0.02 and pK2=11.61±0.03 bymulti-wavelengths spectrophotometry. Potentiometric determination of equilibrium constantswas performed by application of the formation function method. Data analysis program appliedfor multi-wavelengths spectrophotometric determination of acidity constants. Manuscript profile

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