List of Articles Wound Dressing

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  1 - Systematic Review of Wound Dressings: A Movement from the Past to the Present
  Pouriya Norooz Kermanshahi Graça Soares
  10.30495/ijtnbm.2022.692495
  This systematic review aims at investigating different wound dressings commonly used for the healing process and skin repair. Five databases, namely SCOPUS, Web of Science, Medline, Google Scholar, and Cochrane Database of Systematic Reviews, up to 2020, were scanned fo More

  This systematic review aims at investigating different wound dressings commonly used for the healing process and skin repair. Five databases, namely SCOPUS, Web of Science, Medline, Google Scholar, and Cochrane Database of Systematic Reviews, up to 2020, were scanned for papers specific to the topic of concern. The blinded randomized controlled trials, in vivo and in vitro studies comparing common wound dressings, including traditional, natural/biological, and artificial ones were studied in the present review. Finally, the researchers selected 22 studies. From which the data related to the clinical features of wound dressings and their advantages and disadvantages) were derived. The review of literature suggests that many treatment combinations are utilized as wound dressings based on the wound type and hospital guidelines. Nevertheless, there are conflicting views about the most appropriate choice. The findings of the reviewed articles indicate that hydrogels are the most common wound dressing used for wounds and burns due to high thermal/mechanical stability and low water evaporation. However, it is suggested to apply hybrid hydrogel membranes to overcome the low mechanical strength of a single component Manuscript profile
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  2 - Application of Nano Hydrogels In Improving The Performance Of Wound Dressings and Drug Delivery: A Review Study
  MohammadHossein Karami Majid Abdouss MohammadReza Kalaee Omid Moradi
  10.30495/jacr.2023.1982375.2107
  One of the most common clinical diseases is skin scarring, which is defined as damage to the structure or integrity of skin tissue. Nanohydrogel can help in sustained release of drug by entrapping drug or loading drugs and thus promote wound healing. A hydrogel is a thr More

  One of the most common clinical diseases is skin scarring, which is defined as damage to the structure or integrity of skin tissue. Nanohydrogel can help in sustained release of drug by entrapping drug or loading drugs and thus promote wound healing. A hydrogel is a three-dimensional hydrophilic network that is insoluble in water or aqueous solutions and is able to absorb water or other biological fluids that can promote wound healing. Various nano hydrogels have been designed to improve the design of wound dressings, and nano hydrogels are also used in drug release. The advantage of hydrogels over traditional wound dressings is their ability to improve the wound and the wound healing process. Hydrogels meet most criteria for modern wound dressings due to their unique properties. Among the unique properties of nano-hydrogels, we can mention the ability to absorb wound secretions, maintain a moist environment, gas exchange, remove the dressing from the wound surface without pain and replace the dressing for the patient, ease of movement for surgery. In this research, an overview of the use of nano-hydrogels in improving the performance of wound dressings and drug delivery, along with the investigation of antibacterial properties, introduction of commercial wound dressings and wound healing mechanisms, has been discussed. Manuscript profile
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  3 - Design and manufacture of electrospun wound dressing based on polyvinylpyrrolidone fibers modified with aloe vera compounds for the treatment of skin edema
  seyedeh Shadi Amini Dehkordi Nargess Aghamohamadi Javad Shabani Shayeh
  10.30495/jacr.2023.1988101.2129
  In this research, a new type of wound dressing based on polyvinyl pyrrolidone polymer (PVP) modified by extracted compounds from aloe vera (Av) was prepared by electrospinning method. After achieving optimal preparation conditions using experimental design method, the p More

  In this research, a new type of wound dressing based on polyvinyl pyrrolidone polymer (PVP) modified by extracted compounds from aloe vera (Av) was prepared by electrospinning method. After achieving optimal preparation conditions using experimental design method, the prepared material was characterized using infrared Fourier transform spectroscopy, scanning electron microscopy, X-ray diffraction, differential scanning calorimetry analysis, and thermogravimetric analysis. The results of the studies showed that by using the optimal conditions, smooth filament of PVP without node with the diameter of about 100 nm can be achieved. PVP-Av and PVP-Av-Film fiber diameter as well as fibers with a special therapeutic coating were about 105 and 120 nm, respectively with a suitable surface to volume ratio. The results of the investigations showed that the use of polymer coating on the wound dressing not only increase its mechanical resistance, but also increase the hydrophilicity of this wound dressing. In addition, the results of biological investigations showed that this wound dressing has very little toxicity for biological cells and can be used to treat skin edema. Manuscript profile
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  4 - Synthesis and Characterizatin of Polyvinyl Alcohol/Aloe Vera Hydrogel Film by Solvent Casting Method for Wound Dressing Applications
  محبوبه محمودی مونا حاجیان رعنا ایمانی
  In this study, we have tried to make hydrogel films by polyvinyl alcohol and Aloe vera which used in treat wounds. The films were prepared by solvent casting method with different concentration of aloe vera include 20, 30 and 50%. Some properties of samples such as wate More

  In this study, we have tried to make hydrogel films by polyvinyl alcohol and Aloe vera which used in treat wounds. The films were prepared by solvent casting method with different concentration of aloe vera include 20, 30 and 50%. Some properties of samples such as water absorption, degradation rate, water vapour transmission rate and mechanical properties were examined. Also, Fourier transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM) test were carried out in order to identify the bonds and morphological assessment in the samples, respectively. The results showed that with increasing of aloe vera concentration to 30% (PA30), water absorption rate, degradation rate and mechanical properties are increased. In according to SEM investigations, we found with aloe vera increasing, the porosity on surface of samples was increased. In the other hand, water vapour transmission rate have direct comparison with percentage of aloe vera concentration. Finally, cell cytotoxicity and morphology fibroblast cells (L929) attached on the samples surface evaluated by in vitro assay. The results showed that cells proliferated in greater numbers on the PA30 sample compared to other samples. Therefore, our results indicated that polyvinyl alcohol/Aloe vera hydrogel films are a good choice for use in wound dressing. Manuscript profile
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  5 - Recent Biotechnological Advances in the Preparation of Wound Dressings for Diabetics
  Sayed Rasoul Zaker Shahrbanoo Jafari Rahman Emamzadeh
  10.22034/ascij.2023.1986190.1492
  In the last two decades, given the importance of biotechnological drugs and their important role in the treatment of chronic wounds, studies have predicted that the market for advanced wound care targeting surgical wounds and chronic wounds is likely to reach $15-22 bil More

  In the last two decades, given the importance of biotechnological drugs and their important role in the treatment of chronic wounds, studies have predicted that the market for advanced wound care targeting surgical wounds and chronic wounds is likely to reach $15-22 billion by 2024. Therefore, in the present study, the recent advances in biotechnology in the field of preparing wound dressings from compounds obtained from plants and animals for people with diabetic foot ulcers have been discussed. In this research, the methods and approaches of delivery of therapeutic agents for the treatment of DFUs and in fact the recent results of in vitro and in vivo studies, emphasizing the unique potential of wound dressings based on natural polymers in the treatment of DFUs, have been collected and analyzed. This expansion is expected to be driven by advances in technology, increased incidence of chronic wounds, and an increasing elderly population. A review of the challenges ahead in the treatment of chronic wounds reveals the inadequacy of the effectiveness of some wound care products, suggesting that families and governments must contend with medical challenges for longer periods. Diabetic foot ulcer (DFIU) is a chronic ulcer that can cause severe infections and even amputation. Biomaterials that are currently used as matrices for wound healing can be classified into natural and synthetic types according to their origin. Natural biomaterials such as chitosan, alginate, cellulose, hyaluronic acid, silk fibroin, and collagen have been widely recommended for diabetic foot wound healing due to their easy degradability, remarkable biocompatibility, reduced inflammatory responses, and non-immunogenic nature. Biotechnology guarantees the possibility of using natural biomaterials to develop advanced wound dressings with appropriate and patient-friendly therapeutic results.  Manuscript profile