List of Articles Vascular endothelial growth factor

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  1 - Association of Serum VEGF level with Medullary Thyroid Carcinoma in An Iranian Population
  M. Samsam Shariat K. Parivar M. Hedayati P. Yaghmaee
  Vascular endothelial growth factor (VEGF) is a signal protein produced by cells that stimulates vasculogenesis, angiogenesis and lymph angiogenesis. Cancers expressing VEGF are able to grow and metastasize. As thyroid cancer is the most common endocrine cancer and medul More

  Vascular endothelial growth factor (VEGF) is a signal protein produced by cells that stimulates vasculogenesis, angiogenesis and lymph angiogenesis. Cancers expressing VEGF are able to grow and metastasize. As thyroid cancer is the most common endocrine cancer and medullary thyroid cancer (MTC) is an aggressive metastatic cancer, the aim of this study is the relationship between serum VEGF levels and the increased risk of MTC. A descriptive cross-sectional study was conducted, 45 patients with MTC (21 males and 24 females) and 45 healthy persons as control group (24 male and 21 females) were selected. Serum VEGF levels were determined by ELISA technique in both groups. Data analysis was performed using Medcalc 14.8.1 and SPSS22.There was no statistically significant difference in serum VEGF levels between total MTC patients and total control groups, but serum VEGF levels in female MTC group were significantly higher than those in female control group (P Manuscript profile
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  2 - Effect of Six Weeks of Resistance Training on Vascular Endothelial Growth Factor and Neuron Derived Neurotrophic Factor of Heart Tissue in Obese Male Rats
  Neda Ghasemi Mania Roozbayani Hossein Shirvani
  10.22034/ascij.2023.1979919.1468
  The phenomenon of angiogenesis in pathophysiological conditions such as obesity and physiological conditions such as exercise have different effects on the body. The aim of this investigation was to study the effect of six weeks of resistance training on Vascular endoth More

  The phenomenon of angiogenesis in pathophysiological conditions such as obesity and physiological conditions such as exercise have different effects on the body. The aim of this investigation was to study the effect of six weeks of resistance training on Vascular endothelial growth factor and Neuron Derived Neurotrophic Factor in obese male rats. In an experimental study, 20 male wistar rats aged five weeks and weight approximately 120 to 160 grams, were divided into two equal groups, control and experimental, based on weight homogenization. The experimental group performed a training protocol for six weeks, three sessions per week, and each session includes one set of 10 repetitions with a 90-second rest interval, including of climbing a resistance training ladder at a height of one meter and an incline of 85 degrees with a weight attached to the base of the tail (with Paying attention to the maximum weight carrying capacity of each rat. 48 hours after the last training session, the rats were sacrificed and blood was taken from the heart. The values of VEGF and NDNF in the heart tissue were evaluated with ELISA method. In order to examine the changes of between groups, the independent t-test was used at a significance level of p<0.05. The results indicated that six weeks of resistance training led to a significant increase in VEGF values (p=0.0001) and a significant decrease in NDNF values (p=0.0001) in experimental group in comparison to the control group. Base on the findings of this study, it seems that resistance training can have positive effects on preventing the risk of cardiovascular diseases caused by obesity, by increasing some protective factors and reducing angiogenesis inhibitory factors. Manuscript profile