List of Articles Valeriana officinalis

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  1 - Encapsulation of Tribulus terrestris and Valeriana officinalis Extracts in Nanoliposomes and Evaluation of its Antibacterial and Antioxidant Properties
  M. Nouri M. Shafaghi Rad
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  2 - Comparative study of Valeriana Officinalis root extract¸diazepam and ketamin on CNS depressive effects in cats
  رامین Kaffashi Elahi M.H Khayat Nouri جواد Mahmoudi
  Valeriana officinalis is a medicinal plant used in alternative medicine for its sedative and anxiolytic properties. It acts trough GABA receptors increases GABA in synaptic space and stimulates GABA receptors. Ketamine and diazepam also acts trough GABA mechanism but wi More

  Valeriana officinalis is a medicinal plant used in alternative medicine for its sedative and anxiolytic properties. It acts trough GABA receptors increases GABA in synaptic space and stimulates GABA receptors. Ketamine and diazepam also acts trough GABA mechanism but with a different pathway. The purpose of our study was to investigate the sedative effects on cats of valerian extract that extremely beloved by cats in combination with ketamine, and evaluate the possibility of its usage in cats and change the routine methods of anti-anxiety and restraining method. 24 healthy short haired mature male cats randomly selected, fed with standard ration and water ad libitum , were divided into three groups G1, G2, G3, received ketamine(11mg/kg), ketamine-diazepam(1mg/kg), and ketamine-valerian (1250 µg/kg PO) respectively. Rate of CNS depression were evaluated by; onset time of effects, peak score, and duration of peak score, total time of effects and highest recorded score. Scores obtained by ataxia, time at which falling recumbent and pinch test over anus, tail and Achilles tendon. This experiment was conducted as blind. Statistical analysis made by variance analysis (ANOVA) and Tukey test, at a significance level of 5% (p<0.05).Results showed significant effect of valerian on shortening the onset time of effects in compare with G1, and fastest reach to peak score in compare with G1 and G3, peak score duration was much longer than G1 and shorter than G3, onset time of recumbency in G3 was shortest but close to G2. It seems that valerian root extract may be used in combination with ketamine to induce restraining and anti-anxiety effects with shorter dullness and sleepy mood in compare with routine administration of ketamine-diazepam; moreover it is being tolerated well and makes the animal more reliable and friendly with other cats and owners. So this extract may be used instead of diazepam in routine cat restraining protocols.   Manuscript profile
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  3 - Evaluation of growth, yield, and physiological responses of Valeriana officinalis L. to the application of urea, nitroxin, and phosphate Barvar-2 fertilizers
  Mehdi Heydari-Rahni Mohammad Nasri Yousef filizadeh Pourang Kasraei Pezhman Azadi
  10.30495/ejmp.2022.1941956.1656
  In the study, to survey the growth, yield, and physiological responses of valerian (Valeriana officinalis L.) using different concentrations of urea fertilizer (0, 30, 60, 90, and 150 kg.ha-1) and nitroxin and phosphate Barvar-2 bio-fertilizers, an experiment was conduc More

  In the study, to survey the growth, yield, and physiological responses of valerian (Valeriana officinalis L.) using different concentrations of urea fertilizer (0, 30, 60, 90, and 150 kg.ha-1) and nitroxin and phosphate Barvar-2 bio-fertilizers, an experiment was conducted in medicinal Plants farm, Tehran, as a factorial in a randomized complete block design with three replications in the 2019-2020 crop year. Seedling cultivation was carried out in mid-May and urea fertilizer treatment was performed in two stages. To measure root and biological yield, one square meter was harvested from each plot and the dry weight of shoot and root was measured and the sum of these two was calculated as biological yield. Root and rhizome essential oils were extracted by water distillation (Clevenger) and valerenic acid by high performance liquid chromatography (HPLC). Essential oil yield was also calculated based on the essential oil percentage and dry root yield. The average root diameter varied from 7.97 (90 kg urea per ha) to 5.14 mm (control). The highest root yield was obtained in 150 and 90 kg urea.ha-1 along with inoculation with nitroxin and phosphate Barvar-2 (4.88 and 5.1 ton.ha-1, respectively). Application of 90 kg urea.ha-1 along with nitroxin resulted in increased chlorophyll b and total content. Increasing the urea concentration decreased essential oil content and increased essential oil yield. Essential oil content ranged from 0.93 (90 kg urea.ha-1 with nitroxin and phosphate Barvar-2) to 1.94% (no-application of fertilizers). The highest valerenic acid content (0.46% of the extract) and valerenic acid yield (220.27 mg.ha-1) were observed using 30 kg of urea with phosphate Barvar-2 and no application of nitroxin. In general, application of nitroxin and phosphate Barvar-2 bio-fertilizers along with 90 kg urea.ha-1 by improving growth, yield, and physiological traits led to the production of acceptable essential oil and valerenic acid yield. Manuscript profile
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  4 - Enhancement of valerenic acid production in Valeriana officinalis roots by methyl jasmonate -mediated transcriptional changes of sesquiterpene synthase genes
  Hengameh Taheri Mansour Ghesmati
  10.30495/ijpp.2018.545660
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  5 - Enhancement of valerenic acid production in Valeriana officinalis roots by methyl jasmonate-mediated transcriptional changes of sesquiterpene synthase genes
  Hengameh Taheri Mansour Ghesmati
  10.30495/ijpp.2018.541007
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  6 - The effect of salinity and weed allelopathic extract Amaranthus retroflexus and chenopodium album on growth and production of pharmaceutical active Valeriana officinalis
  E. Farajzadeh M. Yarnia V. Ahmadzadeh N. Farjzadeh
          Stress, particularly the combination of them reduction in plant growth and development. However, herb plants have shown resistance to stress. The purpose of this review, the study of the interaction region is important to extra More

          Stress, particularly the combination of them reduction in plant growth and development. However, herb plants have shown resistance to stress. The purpose of this review, the study of the interaction region is important to extract Amaranthus retroflexus and chenopodium album and salinity on germination, growth and yield of root essential oil on valerian. Treatment was extracts of different weeds parts (root, shoot, total plant and control) Salinity levels also defined as control, 4, 8 and 12 ds/m. Maximum negative effect was shoot extract in witout sailinty and 12 ds/m sailinty on germination percent, root, shoot length and leaf area in 4,8 month after emergence and root dry weight. 8 and 12ds/m sailinty reducing germination percent, shoot and root length and leaf area for eight months after emergence, leaf dry weight and root dry weight also.But 4 ds/m salinity drop leaf area in eight months after the green and dry weight of leaves. 4 ds/m salinity only for oil increased. Manuscript profile