List of Articles Sphingosine‌-1-phosphate

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  1 - Investigating the diagnostic value of plasma concentration of adenosine deaminase, sphingosine-1-phosphate and visfatin in the clinical diagnosis of sarcocystosis in small ruminants of Urmia city.
  amir mehmanpasand sohrab rasouli mohamad hosien sadeghi faezeh haidarbeigi soha rezazadeh
  10.30495/vmj.2023.1997237.1028
  Background and purpose: Sarcocystis is an obligate intracellular parasitic protozoan that can cause digestive disorders in patients. It also causes huge financial losses in the livestock industry. Studying the prevalence of this parasite in livestock can lead to increas More

  Background and purpose: Sarcocystis is an obligate intracellular parasitic protozoan that can cause digestive disorders in patients. It also causes huge financial losses in the livestock industry. Studying the prevalence of this parasite in livestock can lead to increased awareness and the possibility of timely prevention in preventing livestock losses. The present study was conducted to study the changes in the biochemical parameters of adenosine deaminase, visfatin, and sphingosine-1-phosphate due to sarcocyst infection in sheep and goats.Materials and methods: During a period of 6 months (from January 2018 to June 2019), blood was drawn from 160 samples (80 sheep carcasses and 80 goat carcasses) that were examined macroscopically and microscopically. The sample size was determined by assuming the average possible prevalence of contamination to be around 90% and a confidence interval of 95%. The carcasses were observed and examined for the presence of rice grain cysts, and after separating the plasma samples, the parameters of adenosine deaminase, visfatin, and sphingosine-1-phosphate were evaluated.Results: Based on the results of this study, all the mentioned parameters in the study patient's goats and sheep had a statistically significant increase compared to the control group (P<0.05).Discussion and conclusion: In general, sarcocysts can cause changes in the plasma levels of adenosine deaminase, visfatin, and sphingosine-1-phosphate. Therefore, it can be used in the biochemical diagnosis (biomarker) of sarcocyst in ruminants with wider studies of the aforementioned parameters along with other plasma parameters. Manuscript profile