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Open Access Article
1 - Investigation of geomechanical parameters of material and rock mass, asmari Formation (Case study: Khersan dam-3 site)
mojtaba Nouri sartangi Gholamreza Lashkaripour Nasser Hafezi Moqadas Mohammad Ghafouri Hossein SadeghiEstimation of resistance parameters of rock mass is one of the most important engineering problems of rock.The study of geomechanical parameters and, finally, the classification of rock masses in the feasibility phase and the initial design of a project, which has very MoreEstimation of resistance parameters of rock mass is one of the most important engineering problems of rock.The study of geomechanical parameters and, finally, the classification of rock masses in the feasibility phase and the initial design of a project, which has very little comprehensive information on the geotechnical properties of rock masses, the amount of stress and the available hydrological characteristics, The main purpose of using a classification system is to classify the parameters and, using their results, provide the nature of the rock mass and its engineering behavior in different conditions. Since rock mass specifications are in the design of drilling, design of retainers, tilt design and other requirements. On this basis, it was considered necessary to obtain the resistance parameters of Khersan 3 Dam site so that, by analyzing these data, the stability of the tunnel, the geomechanical classification of rock mass using the RMR, QI, GSI method can be calculated and the relationship between rock mass resistivity parameters Compare the modulus of elasticity and deformation from different relationships and compare each other. Manuscript profile -
Open Access Article
2 - Engineering geology and engineering classification of rock masses in the site of Gharehpiri dam, NW of Shiraz
Godratolah Farhoudi Jafar Rahnamarad Ali Rahimi Babak Samani Afshin Karimi -
Open Access Article
3 - Waste Mass Movements Analysis of Dash-Kamel area by using the Stereographic Projection (Marzanabad-Chalus freeway)
Saeid Hakimi Asiabar -
Open Access Article
4 - Engineering geological assessment of the Shahid dam site (Semirom, Iran)
Mojtaba Rahimi Shahid Fariba Kargaran bafghi Seyed Mehdi Moosavi Nima Rahimi -
Open Access Article
5 - Study of LncRNA RMRP expression profile and RMRP gene promoter region mutations in breast cancer patients
Majid Sadeghizadeh ملیحه انتظاری Zohreh AkbariBackground: Gene expression ‎regulators and mutations are a kind of biomarker and new ‎therapeutic target for human diseases like cancer. LncRNAs are involved in Several regulatory processes. RNA components of ‎mitochondrial RNA processing ‎endoribonucle MoreBackground: Gene expression ‎regulators and mutations are a kind of biomarker and new ‎therapeutic target for human diseases like cancer. LncRNAs are involved in Several regulatory processes. RNA components of ‎mitochondrial RNA processing ‎endoribonuclease is a lncRNA that its ‎regulatory position has been identified ‎in some cancers. Regarding the importance of the RMRP gene, we are investigating changes in the expression of this gene that are caused by promoter region mutations in breast cancer patients.Methods: In this study, LncRNA RMRP gene expression was evaluated on 25 tumor samples and 25 control samples by semi-quantitative RT PCR technique, and confirmed by Real time PCR technique for a number of samples. Also, to detect the mutation in the promoter region of the LncRNA RMRP gene, DNA extraction and sequencing were performed.Results: The expression of the RMRP gene in tumor samples showed a significant increase relative to control samples. Expression of RMRP gene was shown a significant decrease in positive HER2 samples compared to negative HER2 specimens and a significant increase in positive metastatic tumor samples compared to negative metastatic samples . Also, sequencing of the promoter region revealed differences in the region's sequence in tumor and normal samples.Based on sequencing results, there was no mutation in the RMRP promoter sequence of the tumor .Conclusion: The RMRP gene can be suggested as a tumor and metastatic marker for the detection of breast cancer. But more clinical and molecular research is still needed to prove it more accurately. Manuscript profile -
Open Access Article
6 - Explain the factors affecting stock liquidity using genetic algorithm and minimum and maximum correlation (MRMR) methods
Mahmoud Rezaei Hossein Panahian Mahdi Madanchi Zaj Hasan GhodratiLiquidity of stocks is an important challenge in the capital market. Identifying the factors affecting liquidity helps to predict the stock liquidity situation and thus stock risk management. The purpose of this study is to find the factors affecting the liquidity of st MoreLiquidity of stocks is an important challenge in the capital market. Identifying the factors affecting liquidity helps to predict the stock liquidity situation and thus stock risk management. The purpose of this study is to find the factors affecting the liquidity of stocks. For this purpose, in the first stage, using the research literature and experts, the influencing factors are identified and using the methods of minimum redundancy and maximum correlation (MRMR) and genetic algorithm, the effective variables are selected. In this research, using Excel software and existing raw data, the required data was created and then using support software and neural network toolbox and support vector machine was created. . Finally, the extracted variables using MRMR include stock market value, intensity of product market competition, GDP growth, equity returns, stock returns, inflation rate and family ownership, and using the financial model of financial leverage, government ownership, Equity returns, GDP growth, share buoyancy percentage, market type and board (on the stock exchange and OTC), the intensity of competition in the product market were selected. Manuscript profile