• List of Articles POF

      • Open Access Article

        1 - Effect Of Anesthesia with PropOfol Following Premedication Vitamin C in Dogs
        Mehdi Marjani Hamed Alizadeh Seyyed Emade Mirza Ghafour
        Inroduction and Objective:Propofol is an intravenous anesthetic agent that is very useful today and is administered intravenously. Effect of Vitamin C on the central nervous system are similar to amphetamines is the moderation of central nervous system. The purpose of t More
        Inroduction and Objective:Propofol is an intravenous anesthetic agent that is very useful today and is administered intravenously. Effect of Vitamin C on the central nervous system are similar to amphetamines is the moderation of central nervous system. The purpose of this study was to investigate the effect of propofol anesthesia following treatment with vitamin C in male dogs.Materials andMethods:In this experimental study, 25 dogs were divided into 5 groups. Group 1 as control (no treatment), and group 2 and anesthetic with propofol group 3 to 5, respectively treated with 100 ,250, 500µg/kg of body weight dose of vitamin C and then anesthetized with propofol. Pre and postoperative vital signs including heart rate, respiratory rate, and rectal temperature were recorded during anesthesia. Before and after anesthesia vital signs including heart rate, respiratory rate, rectal temperature and anesthesia time were recorded.Results:The comparison of parameters before and after of anesthesia induction don’t show significant differences between the experimental and control group. Moderate doses of vitamin C leads to a decrease in body temperature after the anesthesia induction. On the other hand, high doses of vitamin C leads to a reduction in the duration of anesthesia compared with control group.Conclusion:High-dose of vitamin C can be used as pre-anesthetic in dogs which there are long-term risks of anesthesia Manuscript profile
      • Open Access Article

        2 - Investigating the effects of injecting intravenous anesthetics Propofol, sodium thiopental, fentanyl during implantation on the rate of abnormalities in rats.
        Shiva Shojaifard Mohamad Reza Jamshidi Elham Hosseini Somayeh Abdollahi sabet مهدی رهنما
        Background & Aim: Background and purpose: Anesthesia is very important for assisted reproductive technology to provide minimal adverse effects on the oocyte. Defects in the development of the embryo or abnormality in its growth phenomenon lead to IVF failure in most More
        Background & Aim: Background and purpose: Anesthesia is very important for assisted reproductive technology to provide minimal adverse effects on the oocyte. Defects in the development of the embryo or abnormality in its growth phenomenon lead to IVF failure in most cases. The number of abnormalities in laboratory rats is RAT.Materials & methods: Propofol, Nestonal, and Fentanyl were used for single and combined anesthesia. The sham group was studied to control injection stress by injecting distilled water and the control group without receiving drugs. In the next step, the fertility conditions of the mice were provided. The effectiveness of the drugs is relatively similar to the selected doses, and after counting, cesarean surgery is performed on each fetus, and after the placenta is carefully separated from the fetus, both are carefully weighed, measured, and recorded.Results: The difference in the number of births was not observed, but the weight of the placenta and the weight of the fetus were investigated as indicators determining the effect of drugs on the fetus, which can be a symbol of fetal abnormalities. The results showed that the drugs used had no effect on conception and its success rate, but they were effective on fetal growth, and propofol had the least effect on abnormalities, and there was a significant difference in placenta and fetal weight between this group and the other group. The birth weight of mice was based on the type of drug, the highest birth weight was related to the drug Nestonal (TP) and the lowest birth weight was related to the drug Fentanyl (PH). Based on the type of drug, the live birth weight of the mice was the highest weight of the live mice related to Nestonal drug (TP) and the lowest was related to Fentanyl drug (PH).Conclusion: Examining anesthetic drugs to find the safest and best drug is of great clinical and research importance. The study of chromosomal abnormalities is one of the main programs of future studies for the analysis of fetal abnormalities. Manuscript profile
      • Open Access Article

        3 - Ultrasonographic measurement of canine aorta and aortic inlet before and after administration of Propofol
        Gh Assadnassab Gh Mousavi مهرداد Neshat Gharamaleky
             Induction of safe anesthesia is an important task in veterinary medicine. One of the drugs used for anesthesia is Propofol. In this study, five healthy German shepherd dogs were selected and standard echocardiographic procedure from the right paraste More
             Induction of safe anesthesia is an important task in veterinary medicine. One of the drugs used for anesthesia is Propofol. In this study, five healthy German shepherd dogs were selected and standard echocardiographic procedure from the right parasternal axis view conducted to observe the aorta and aortic inlet in B-mode and M-mode display formats before and after anesthesia with 6 mg/kg of Propofol. In the short axis view, the dorso-ventral and transverse diameter of the aorta in B-mode display and in the long axis view, the systolic and diastolic diameter of the aortic inlet in M-mode display were measured. The average dorso-ventral and transverse diameter of aorta in normal dogs was 22.77±1.49 mm and 20.75± 1.34 mm respectively while in anesthetized dogs these figures were 22.02±0.87 mm and 20.64±1.19 mm respectively which were not significantly different from normal dogs. However, the mean diameter of aorta inlet in M-mode display during systole and diastole was 15.62±0.84 mm and 15.31±0.68 mm respectively in normal dogs and for anesthetized animals these figures were 21.60±1.23 mm during systole and 19.70±0.68 mm during diastole which were significantly different compared with the normal dogs.  Manuscript profile
      • Open Access Article

        4 - Protein- Protein Interaction network analysis for Discovering Potent Candidate Drugs in Female Infertility
        Parinaz Tabrizi-Nezhadi Habib MotieGhader masoud Maleki
      • Open Access Article

        5 - Protein- Protein Interaction network analysis for Discovering Potent Candidate Drugs in Female Infertility
        Parinaz Tabrizi-Nejhadi Habib MotieGhader Masoud Maleki
      • Open Access Article

        6 - Echocardiographic evaluation of cardic index functional effects of different dose propofol in mixed breed dog
        Farshad Najjar Asianani Mehdi Tavana mehrdad yadegari dehkordi
        Summary: Propofol as an intravenous anesthetic agent can be short-term and ambulatory surgical facilities as well as the lack of artificial respiration very helpful. The aim of this study was to evaluate the effects of treatment techniques using echocardiography as a no More
        Summary: Propofol as an intravenous anesthetic agent can be short-term and ambulatory surgical facilities as well as the lack of artificial respiration very helpful. The aim of this study was to evaluate the effects of treatment techniques using echocardiography as a noninvasive technique based on functional and structural heart. 10 adult male dogs, 2-3 years old and weighing 22.5±2.5 kilograms were used in this study. Cardiovascular health was evaluated using echocardiography, auscultation and electrocardiography. 1 mg/kg propofol intravenous were injected and LVDd, LVDs, SV, EF, FS, Ws and HR were examined. After one week rest for animals 2.5 mg/kg propofol were injected intravenously and the factors were evaluated again. Based on the results in 1mg/kg injection group FS and EF was significantly decreased in compared with the control group and there were no significant change in cardiac functional parameters in 2.5 mg/kg injection group. Keyword: Propofol, Dog, Echocardiography, Anesthesia, hart Manuscript profile
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        7 - مدیریت کود در مزارع برنج از طریق کاربرد باکتری‌های محرک رشد گیاه
        هاشم امین پناه سعید فیروزی
        این آزمایش مزرعه­ای در ایستگاه تحقیقات برنج تنکابن، ایران، به منظور بررسی اثر کاربرد باکتری­های محرک رشد گیاه بصورت بذرمال بر رشد و عملکرد برنج در سطوح متفاوت کود شیمیایی نیتروژن انجام شد. این آزمایش به صورت فاکتوریل دو عاملی و در قالب طرح پایه بلوک­های کامل More
        این آزمایش مزرعه­ای در ایستگاه تحقیقات برنج تنکابن، ایران، به منظور بررسی اثر کاربرد باکتری­های محرک رشد گیاه بصورت بذرمال بر رشد و عملکرد برنج در سطوح متفاوت کود شیمیایی نیتروژن انجام شد. این آزمایش به صورت فاکتوریل دو عاملی و در قالب طرح پایه بلوک­های کامل تصادفی با سه تکرار انجام شد. فاکتورهای مورد بررسی شامل کاربرد باکتری­های محرک رشد گیاه (ازتوباکتر کروکوکوم، آزوسپریلوم لیپوفروم، کاربرد توام ازتوباکتر کروکوکوم و آزوسپریلوم لیپوفروم و عدم کاربرد باکتری­های محرک رشد گیاه) و مقدار کود نیتروژن (50، 75 و 100 درصد مقدار کود شیمیایی نیتروژن توصیه شده، به ترتیب برابر 50 ، 75 و 100کیلوگرم نیتروژن در هکتار) بودند. نتایج نشان داد که حداکثر مقدار عملکرد شلتوک (7875 کیلوگرم در هکتار) در پلات­های تیمار شده با کاربرد توام باکتری ازتوباکتر کروکوکوم و آزوسپریلوم لیپوفروم مشاهده شد، در حالی­که حداقل عملکرد شلتوک در تیمار شاهد عدم مصرف باکتری مشاهده شد. همچنین نتایج نشان داد که با افزایش مصرف نیتروژن از 50 به 100 کیلوگرم در هکتار، عملکرد دانه، تعداد خوشه در متر مربع، تعداد پر در خوشه و وزن هزار دانه به ترتیب 9، 9، 18 و 6 درصد افزایش یافت. حداکثر عملکرد (7875 کیلوگرم در هکتار) با مصرف نیتروژن به میزان 75 کیلوگرم در هکتار و کاربرد توام باکتری ازتوباکتر کروکوکوم و آزوسپریلوم لیپوفروم مشاهده شد.  Manuscript profile
      • Open Access Article

        8 - Experimental Study of Modulus of Elasticity, Capillary absorption of water and UPV in Nature-Friendly Concrete Based on Geopolymer Materials
        Mohammadhossein Mansourghanaei Morteza Biklaryan Alireza Mardookhpour
      • Open Access Article

        9 - The Evaluation of Serum Lipids and Oxidative Stress Indices Following Propofol Administration in Broilers
        Maryam Karimi Dehkordi Majid Gholami-Ahangaran Pardis Banimehdi
        The oxidative stress is one of the side effects of anesthesia. This study aimed to evaluate the changes in oxidative stress indices following propofol administration in broilers. For this purpose, 90 Ross broiler chicks were divided into two main and control groups. Ane More
        The oxidative stress is one of the side effects of anesthesia. This study aimed to evaluate the changes in oxidative stress indices following propofol administration in broilers. For this purpose, 90 Ross broiler chicks were divided into two main and control groups. Anesthesia was induced by the injection of 2 mg propofol per kg of bird weight, intra-bone injection to induce anesthesia, and 0.5 mg propofol per kg bird weight to continuous anesthesia. To evaluate the serum lipids and oxidative stress indices (catalase activity, malondialdehyde concentration, and total antioxidant capacity), blood sampling was performed before anesthesia, during anesthesia, and 24 hours after the anesthesia. The results showed that the activity of serum catalase in 24 h after anesthesia (129.5 ± 6.69) was significantly higher than control chickens and its level during anesthesia (112.9 ±5.04), and before anesthesia (120.9 ± 4.21). The malondialdehyde concentration did not increase during anesthesia (34.3 ± 1.54), whereas it significantly increased 24 h after anesthesia (42.8 ± 4.28). Total antioxidant capacity significantly decreased 24 h after anesthesia (19.2 ± 1.67) compared to before (25.9 ± 1.27) and during anesthesia (27.4 ± 1.37). Total antioxidant capacity significantly increased before and during anesthesia compared to 24 h after anesthesia. Serum lipid indices did not change during the experiment. In general, this study's results showed that although using propofol in broiler chickens during anesthesia can effectively neutralize free radicals and prevent the side effects of oxidative stress, after anesthesia, oxidative stress indices increase. Manuscript profile