• List of Articles Octapamine

      • Open Access Article

        1 - The effect of bitter orange peel compounds and physical activity on physical performance and health
        Sarvenaz Aliasgari Mohammad Ali Azarbayjani Sirvan Atashak Maghsoud Peeri Saleh Rahmati
        The use of phytochemical compounds in herbs has increased in recent decades. Currently, some herbs are used to improve physical performance and body composition. Evidence shows that the health-enhancing benefits of herbs are caused by their bioactive compounds such as p More
        The use of phytochemical compounds in herbs has increased in recent decades. Currently, some herbs are used to improve physical performance and body composition. Evidence shows that the health-enhancing benefits of herbs are caused by their bioactive compounds such as polyphenols, terpenoids and alkaloids on the body's biological systems. Bitter orange peel has attracted the attention of researchers as one of the effective and widely used plants for physical performance and weight control due to its alkaloid compounds including synephrine and octepamine. Literature review show that by activating β3-adrenergic receptors, Synephrine increases lipolyzed and availability of fatty acids for peripheral tissues, especially skeletal muscles, increases the process of fatty acid oxidation and reduces the oxidation of carbohydrates. The result of these changes is saving muscle glycogen consumption (glycogen sparing) and delaying fatigue. On the other hand, Synephrine reduces appetite by acting on the neuromedin U2 receptor, and simultaneously with the development of thermogenesis, it causes weight loss. Although the effects of the compounds in orange peel on physical performance and weight control are contradictory, the need for more studies regarding the effect of these compounds is necessary. Manuscript profile
      • Open Access Article

        2 - A review on determining the effect of aerobic exercise and octapamine supplementation on vascular function following metabolic disorders
        fatemeh shokri Mohamad ali Azarbayjani Maghsood Peeri Farshad Ghazalian
        Background: Obesity, which is a characteristic of metabolic syndrome. Based on this, obese people are in a mild inflammation condition due to abnormal secretion of inflammatory mediators. There are several mechanisms for the occurrence of this inflammation, the most imp More
        Background: Obesity, which is a characteristic of metabolic syndrome. Based on this, obese people are in a mild inflammation condition due to abnormal secretion of inflammatory mediators. There are several mechanisms for the occurrence of this inflammation, the most important of which is the increasing production of inflammatory mediators and the reduction of anti-inflammatory mediators. Deep-heated oils, as an integral part of the diet, are one of the causes of inflammation in obesity. Studies show that with the development of obesity, capillary formation in adipose tissue does not occur in line with changes in cell size. Therefore, fat tissue in obese people is always associated with lack of oxygen and the secretion of inflammatory mediators causes systemic inflammation.Methods: To conduct the present study, the keyword terms Aerobic Exercise, Metabolic disorders, and Octapamine were searched in all databases, including Science of Web, Pubmed, Google, Magiran, SID.IR, scholar risk factors, etc., with no year restrictions. The articles were then categorized based on the effect of performing aerobic exercise and octapamine supplementation on vascular function following metabolic disorders.Findings: The results show that aerobic exercise and octapamine supplementation improve the process of angiogenesis of visceral fat tissue that has been disrupted by deep-fried oils and reduces the damage caused by feeding with deep fried oils.Conclusions: Taking deep-heated oils leads to disturbances in fat metabolism in visceral fat tissue, and in this condition, capillary formation in visceral fat tissue decreases significantly and insulin resistance increases. As a result, this is associated with functional disorders of visceral fat tissue. However, aerobic exercise and octapamine improve the angiogenesis process of visceral fat tissue and reduce the damage caused by feeding with deep-heated oils. Manuscript profile