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      • Open Access Article

        1 - Numerical solution of the spread of infectious diseases mathematical model based on shifted Bernstein polynomials
        Farshid Mirzaee Seyede Fatemeh Hoseini Sahar Alipour
        The Volterra delay integral equations have numerous applications in various branches of science, including biology, ecology, physics and modeling of engineering and natural sciences. In many cases, it is difficult to obtain analytical solutions of these equations. So, n More
        The Volterra delay integral equations have numerous applications in various branches of science, including biology, ecology, physics and modeling of engineering and natural sciences. In many cases, it is difficult to obtain analytical solutions of these equations. So, numerical methods as an efficient approximation method for solving Volterra delay integral equations are of interest to many researchers. In this paper, a numerical method is developed for solving the Hammerstein–Volterra delay integral equation by least squares (LS) approximation method, which is based on Shifted Bernstein polynomials (BPs). This equation is a mathematical model for the spread of certain infectious diseases with a constant rate that varies seasonally. Least squares method is a mathematical model for data fiting which minimizes the sum of squared the difference between an observed value and the value provided by a model. In this paper, the shifted Bernstein polynomials are introduced and then approximation of an arbitrary function by using these polynomials is presented . Also, the Hammerstein–Volterra delay integral equation is introduced and the details of least squares method for solving a mathematical model is presented. Finally, we show the efficiency of the proposed method by solving two numerical examples and comparing the results with other methods. Manuscript profile
      • Open Access Article

        2 - Natural marine products are a source of new drugs
        Lida Shojaei kavan
        Natural products from plants, animals, microbes and minerals have long been a traditional source for treating human diseases. Recent advances in analytical, spectroscopic, and high-throughput screening technology have greatly revived the discovery of natural drugs, incl More
        Natural products from plants, animals, microbes and minerals have long been a traditional source for treating human diseases. Recent advances in analytical, spectroscopic, and high-throughput screening technology have greatly revived the discovery of natural drugs, including the contribution of marine products-based drugs. The marine environment is a unique resource that contains enormous biological diversity and may potentially lead to successful treatments. An increasing number of compounds from marine sources are entering clinical trials, and thus, the field's impact on the pharmaceutical industry is increasing. Marine organisms are excellent producers of natural chemicals with diverse structures and pharmacological activities. Most of the new products being produced from the sea are anti-tumor, anti-inflammatory and anti-infectious products. Invertebrates and seaweeds are diverse and at the same time rich sources of biologically active substances for the production of new drugs. Despite all the efforts made to isolate new drugs from the sea, due to the obstacles in the way of the mass production of these drugs, including the limitation of the reserves of marine organisms, the cultivation and propagation of these organisms and the isolation of medicinal substances from them, in the realm of experience and The test remains. However, according to the progress of science, marine medicines have a very bright perspective and will lead to the creation and expansion of effective treatment methods in the medical field in the near future. Manuscript profile
      • Open Access Article

        3 - Explaining the Resilience of Cities Against Infectious Diseases (Covid-19) (The Case Study of Zanjan)
        mohamad taghi heydari mohammad rasoli sharareh saidpour
        The growing trend of urbanization in the years after the Industrial Revolution reduced the capacity of cities to meet the needs of citizens and their capabilities. In this regard, the occurrence of unexpected events such as the Corona outbreak has raised the need to mea More
        The growing trend of urbanization in the years after the Industrial Revolution reduced the capacity of cities to meet the needs of citizens and their capabilities. In this regard, the occurrence of unexpected events such as the Corona outbreak has raised the need to measure the flexibility of cities to establish a proportion between the container and the urban content. Although the outbreak of Corona is an unexpected event, in recent years cities have been warned through SARS that human society in general and cities, in particular, should adopt policies against events such as high-prevalence infectious diseases, but so far the issue of infectious diseases in cities has not been addressed, so when cities face such incidents, more confusion and disability are displayed. The present study aims to identify cities against infectious diseases, identify all the effects that infectious diseases can have on cities, and finally provide the best coping strategies. For this purpose, the documentary-field method has been used to collect information and for analysis and evaluation, FEMA and FAAO techniques have been used and GIS has been used for graphical representation. The results of the research have shown that; closure of small businesses, the inability of the poor to provide for their livelihoods, loss of socio-spatial justice in the distribution and use of services, adverse psychological effects on citizens at risk of disease, and reverse effects of public transportation on disease, scarcity, and hoarding of food-therapy, closure and suspension of educational activities, the disorder of urban management institutions to deal with the Covid-19, reverse effect of congestion growth against the infectious disease, have been the most important effects of infectious disease on cities, in this regard, actions to control and resilience of the city before and after failure have been presented. The obtained results have been proved to be successful. Manuscript profile
      • Open Access Article

        4 - Prevalence of infectious diseases in Bushehr port during the constitutional period
        zahra morovati AliAkbar khedrizadeh
        The people of the port of Bushehr suffered from a wide range of infectious diseases during the turbulent days of the constitution. The prevalence of these diseases was one of the social realities of the Qajar era. In contrast to the existing traditional infrastructure, More
        The people of the port of Bushehr suffered from a wide range of infectious diseases during the turbulent days of the constitution. The prevalence of these diseases was one of the social realities of the Qajar era. In contrast to the existing traditional infrastructure, little effective treatment had little effect on reducing mortality. This article shows the prevalence of these diseases in Bushehr port based on the contents of press, archival documents and historical sources using the method of historical research based on description and analysis. The present study aims to investigate the types of infectious diseases and the factors affecting its prevalence in Bushehr. This study seeks to answer the question that the prevalence of various infectious diseases in Bandar Bushehr has been influenced by what factors? Numerous factors such as lack of attention of port people to personal and social health, lack of safe drinking water, improper burial of patients and improper performance of government officials in the face of diseases, are important factors in the prevalence of infectious diseases in this it is closed. Manuscript profile
      • Open Access Article

        5 - High resolution melting (HRM) curve analysis for rapidly and accurate determination of Salmonella spp. with invA gene
        hasan Nili seyed ali ghorashi Habibollah Dadras mohammad Sadegh Saeiabadi
        Background & Objectives: Salmonellosis is an infectious and common disease between humans and animals that is caused by different strains of Salmonella. Progress in molecular diagnostic methods, has led to accurate and easy detection and characterization of food mic More
        Background & Objectives: Salmonellosis is an infectious and common disease between humans and animals that is caused by different strains of Salmonella. Progress in molecular diagnostic methods, has led to accurate and easy detection and characterization of food microbial agent. The purpose of this research was to use HRM technique to access more accurate and rapid diagnosis of Salmonella bacteria by means of invA gene. Material & Methods: In this study, diagnosis of Salmonella was done by polymerase chain reaction and high resolution melting curve ( PCR-HRM) using the sequence on invasion A gene (invA) as a marker.       In total 9 Salmonella reference strains using a specific primer pair of genes invA were used to detect Salmonella.   Results: The expected size of PCR amplified fragments of invA gene was determined as 284bp. All tested strains were able to show a Salmonella specific melting curve with high resolution at thermal interval of 87.8-87.9°C. Conclusion: The results showed that HRM using specific primers of invA gene can be used as an accurate and reliable technique for diagnosis Genus of Salmonella. Manuscript profile