• List of Articles Citrulline

      • Open Access Article

        1 - Comparison of the effect of short-term consumption alone and a combination of L-arginine and L-citrulline supplements on aerobic and anaerobic capacity of young football players
        abolfazl ghodsi abas mehranpour bahram abedi Mojtaba khansooz
        AbstractObjective: The present study was conducted with the aim of comparing the effect of short-term use alone and a combination of L-arginine and L-citrulline supplements on the aerobic and anaerobic capacity of young soccer players.Materials and Methods: n this semi- More
        AbstractObjective: The present study was conducted with the aim of comparing the effect of short-term use alone and a combination of L-arginine and L-citrulline supplements on the aerobic and anaerobic capacity of young soccer players.Materials and Methods: n this semi-experimental study, which was conducted with a pre-test-post-test design, 60 young male soccer players with an age range of 15 to 18 years were selected as available and in 4 groups of 15 L-arginine supplement, L-citrulline supplement, combined of L-arginine, val-citrulline supplement and placebo. In the pre-test and post-test stages, the aerobic and anaerobic power of the subjects was measured using yo-yo tests and RAST test. The period of supplement consumption was for 7 days. The amount of L-arginine and L-citrulline supplements alone was 2.4 grams per day, and in the combined group, each of the supplements consumed 1.2 grams.Findings: Short-term consumption (7 days) of L-arginine supplement, L-citrulline supplement and a combination of L-arginine and L-citrulline supplement on increasing aerobic power, peak anaerobic power, average anaerobic power, minimum anaerobic power and reducing the fatigue index of football players Young people have a significant effect (P>0.05). Other results indicate the greater effect of the combination of L-arginine and L-citrulline supplements compared to L-arginine and L-citrulline supplements alone in improving the aerobic and anaerobic capacity of young soccer players.Conclusion: Based on the findings of the present study, it can be concluded that the combined use of L-arginine and L-citrulline supplements can be effective in increasing the aerobic and anaerobic capacity of young football players.. Manuscript profile
      • Open Access Article

        2 - Phytochemical evaluation and antioxidant and inhibitory effects of Citrullus colocynthis L. extract on the production of amyloid nano–biofibrils from bovine serum albumin as a model protein
        Hourieh Mansouri amir arasteh Ramazan Ali Khavari-Nejad
        Colocynth with the scientific name of Citrullus colocynthis L. is one of the plants that it's anti–oxidant and anti–diabetic effects has been shown in previous research. In this study, in addition to the phytochemical study of hydro–alcoholic extract o More
        Colocynth with the scientific name of Citrullus colocynthis L. is one of the plants that it's anti–oxidant and anti–diabetic effects has been shown in previous research. In this study, in addition to the phytochemical study of hydro–alcoholic extract of Colocynth, its anti–oxidant and inhibitory effects on the production of amyloid nanobiofibrils from bovine serum albumin as a model protein have been investigated. The fruit of the plant was collected from the desert areas around Qom in the fall of 2017, dried and then extracted by maaceration method. Analysis of secondary compounds of the extract was performed by gas chromatography-mass spectrometry and the amount of its most important compounds including citrulline and citronellol was obtained by HPLC. The antioxidant activity of the extract was evaluated using DPPH method and then the amyloid fibrils were prepared in the test tube at high temperature and low pH and electron microscope imaging was used to confirm the presence of the fibrils. Congored spectroscopy was used to investigate the inhibitory effects on the production of amyloid fibrils. The results showed that methyl beta-galactopyranoside and beta-diglucopyranoside with 29.51% and 6.31% respectively, were the most abundant chemical compounds and tetradcanoic acid with 16.31% and then octa and hexadecanoic acid with respectively 14.11% and 10.94% were the most compounds found in the extract. The levels of citrulline and citronellol in the extract were 0.0041 and 0.013 mg, respectively. The highest anti–oxidant activity was in the concentration of 10 mg/ml of the extract with 71.5% and the highest inhibition of production of amyloid fibers in the concentration of 1 mg/ml and 99% were seen. Colocynth extract with the presence of potent anti–oxidant compounds and its inhibitory effects on the production of amyloid fibrils, will be very useful in preventing and reducing the incidence of Alzheimer's disease. Manuscript profile