List of Articles Anti-cancer effects

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  1 - Study of antioxidant effect of rosemary leaf extract (Rosmarinus officinalis) and strawberry fruit extract (Fragaria vesca) on stomach cancer cells
  Mehdad Enkari Samira Goodarzi Kiana Ansari
  Purpose and Problem: Stomach cancer is one of the most common cancers in the world that causes many deaths among humans. The aim of this study was to investigate the antioxidant effect of rosemary leaf extract (Rosmarinus officinalis) and strawberry (Fragaria vesca) on More

  Purpose and Problem: Stomach cancer is one of the most common cancers in the world that causes many deaths among humans. The aim of this study was to investigate the antioxidant effect of rosemary leaf extract (Rosmarinus officinalis) and strawberry (Fragaria vesca) on stomach cancer cells. Method: After preparing two plant substances and extracting them, measure the antioxidant power of iron regeneration (FRAP), the toxicity of the two plant extracts used on the growth and proliferation of cancer cells and fibroblasts in concentrations. 0.5, 1, 1.5 and 2 mg/ml were measured by MMT method and IC50 was measured in two plant extracts for 24, 48, 72 and 96 hours. One-way analysis of variance with a significance level of 0.05 was used to analyze the results. Results: The results showed that the highest FRAP levels for strawberry fruit and rosemary leaf extracts in water solvent were 1.68 ± 0.08 and 0.94± 0.15, respectively. The results showed that 2mg /ml for rosemary leaf extract and strawberry fruit has the best effect to prevent the growth and proliferation of cancer cells and fibroblasts. The values obtained for IC50 showed that the concentration required to inhibit 50% of the antioxidant activity for the two extracts at 96 h was the lowest. Conclusion: The results showed that both extracts have anti-cancer effects on AGS cell line in Stomach cancer that strawberry fruit has a more suitable effect than rosemary leaf.   Manuscript profile