• List of Articles Neuron

      • Open Access Article

        1 - Comparing of the antisocial and borderline personality disorder, empathy, and mirror neuron function in pepole with secure and insecure attachment styles
        Masoumeh Zarei Nasser Goodarzi Nader Monirpour
        The purpose of this study was to compare antisocial and borderline personality disorder, empathy, and mirror neuron function in chronic addicts and non-addicts with secure and insecure attachment styles. The research method is causal-comparative. The statistical populat More
        The purpose of this study was to compare antisocial and borderline personality disorder, empathy, and mirror neuron function in chronic addicts and non-addicts with secure and insecure attachment styles. The research method is causal-comparative. The statistical population of this study consisted of all opioid addicts (opium and heroin addicts) who were referred to addiction treatment centers in Tehran in 2019. Sampling method was purposive sampling. The research instruments included the Hazen & Shaver Attachment Style Questionnaire (1987), Davies Empathy Questionnaire (1983), the Millon 3 Clinical Multidisciplinary Questionnaire, and electroencephalography apparatus. Data were analyzed using multivariate analysis of variance. Results of data analysis showed that main effect of attachment styles was significant (p <0.05). Accordingly, the differences between the two groups of secure and insecure attachment styles in antisocial personality, borderline personality, empathy, and mirror neuron function in the cz channel were confirmed. Accordingly, in both groups of addicts and non-addicts, insecure attachment style had a greater effect on antisocial personality, borderline personality, empathy, and mirror neuronal function in the cz channel. . Also, people with a secure attachment style from a psychoanalytic perspective have a better ability to control their transient needs and behavioral impulses. Benefiting from a strong super ego allows the individual to manage and control the emotions and impulses of the id more powerfully. Postponement of immediate and transient needs draws human attention and concentration to the satisfaction of more important and long-term needs that play an effective role in a person's mental health, as well as the amount of neurotic anxiety caused by interpersonal conflicts. It focuses on the behavior and reduction of impulsive behaviors in these people. Manuscript profile
      • Open Access Article

        2 - The Effect of Risperidone on the Induction of Psychological Dependence and the Number of Hippocampal Neurons in Adult Male Rats
        Zahra Mansouriarani Nasrin Heydariyeh Hamid Reza Banafshe Gholamreza Ghavipanjeh Majid Lotfinia
        Psychological dependence on substances is the desire to consume substances or something that has pleasurable effects and produces satisfaction. Various substances cause this dependence. Previous studies indicate the possible effect of risperidone on the brain reward sys More
        Psychological dependence on substances is the desire to consume substances or something that has pleasurable effects and produces satisfaction. Various substances cause this dependence. Previous studies indicate the possible effect of risperidone on the brain reward system and the involvement of different receptors in conditioned place preference (CPP). Therefore, the present study was designed with the aim of investigating the effect of risperidone on the induction of psychological dependence and the number of hippocampal neurons. For this study, 40 male Wistar rats with a weight range of 230-280 grams were used. Risperidone was injected intraperitoneally with doses of 1, 2 and 4 mg/kg. At the end of the hippocampus experiments, the animals were taken out and fixed by formalin, then cut and after staining, they were used for histological evaluation and neuronal counting. The results of this study showed that the administration of risperidone with a dose of 2 and 4 mg/kg causes a significant increase in CPP (p < 0.05). Also, in histological evaluation, no neuronal destruction was observed in all risperidone groups (1, 2 and 4 mg/kg). According to the obtained results, it can be concluded that risperidone in higher doses causes an increase in conditioned place preference and learning and dependence and should be considered in treatment. Manuscript profile